Results 91 to 100 of about 613,936 (286)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
MathematicsGraph data mining has emerged as a prominent area of research in both academic and industrial domains. Dynamic link prediction, a critical subfield within graph data mining, offers a more realistic representation of real-world networks compared to static
Mengdi Sun, Minghu Tang
doaj +1 more source
Applying the take-grant protection model [PDF]
, 1990 The Take-Grant Protection Model has in the past been used to model multilevel security hierarchies and simple protection systems. The models are extended to include theft of rights and sharing information, and additional security policies are examined ...
Bishop, Matt
core +2 more sources
Dynamics Based Privacy Protection for Average Consensus on Directed Graphs
CoRR, 2018 Average consensus is key for distributed networks, with applications ranging from network synchronization, distributed information fusion, decentralized control, to load balancing for parallel processors. Existing average consensus algorithms require each node to exchange explicit state values with its neighbors, which results in the undesirable ...
Huan Gao, Yongqiang Wang 0001
openaire +2 more sources
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Energies, 2018 Regional protection based on multisource information of a regional power network depends on communication technology. A partition strategy considering communication constraints and implementation techniques must be considered to realize the regional ...
Zhenxing Li +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Single failure resiliency in greedy routing [PDF]
, 2013 Using greedy routing, network nodes forward packets towards neighbors which are closer to their destination. This approach makes greedy routers significantly more memory-efficient than traditional IP-routers using longest-prefix matching.
Colle, Didier +4 more
core
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Heuristic Solution to Protect Communications in WDM Networks using P-cycles [PDF]
, 2007 Optical WDM mesh networks are able to transport huge amount of information. The use of such technology however poses the problem of protection against failures such as fibre cuts.
Cousin, Bernard +2 more
core +3 more sources