Results 1 to 10 of about 51,241 (256)

Node Immunization with Time-Sensitive Restrictions [PDF]

Sensors, 2016
When we encounter a malicious rumor or an infectious disease outbreak, immunizing k nodes of the relevant network with limited resources is always treated as an extremely effective method.
Wen Cui, Xiaoqing Gong, Chen Liu, Dan Xu, Xiaojiang Chen, Dingyi Fang, Shaojie Tang, Fan Wu, Guihai Chen   +8 more
doaj   +6 more sources

Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization [PDF]

Cell Reports, 2020
Summary: Generating robust CD4+ T-helper cell type 1 (Th1) responses is essential for protective vaccine-induced type 1 immunity. Here, we examine whether immunization formulation associated with enhanced vaccine efficacy promotes antigen targeting and ...
Jeffrey Lian, Aleksandra J. Ozga, Caroline L. Sokol, Andrew D. Luster   +3 more
doaj   +5 more sources

Using Proxies for Node Immunization Identification on Large Graphs

IEEE Access, 2017
Given a large graph, like a social network, which k nodes should be immunized (or removed) to make the network safe from the spread of a virus? This is the node immunization problem. One of the classical methods, inspired by immunology, in analyzing this
Raymond Ahn, Justin Zhan
doaj   +4 more sources

Targeted Lymph Node Immunization with Serotype-Specific Dengue VLP Vaccines Enhances Antibody Avidity and Specificity [PDF]

Vaccines
Introduction: Dengue virus (DENV) remains a global health threat, with four distinct serotypes (DENV1-4) that complicate vaccine development due to low-affinity, cross-reactive antibodies that increase the risk of antibody-dependent enhancement (ADE ...
Dominik A. Rothen, Alessandro Pardini, Sudip Kumar Dutta, Pascal S. Krenger, Anne-Cathrine Vogt, Romano Josi, Monique Vogel, Paul Engeroff, Mona O. Mohsen, Kaspars Tars, Byron Martina, Martin F. Bachmann   +11 more
doaj   +2 more sources

Immunization of epidemics in multiplex networks. [PDF]

PLoS ONE, 2014
Up to now, immunization of disease propagation has attracted great attention in both theoretical and experimental researches. However, vast majority of existing achievements are limited to the simple assumption of single layer networked population, which
Dawei Zhao, Lianhai Wang, Shudong Li, Zhen Wang, Lin Wang, Bo Gao   +5 more
doaj   +1 more source

Research on Microblog Rumor Immunization Strategy [PDF]

Jisuanji gongcheng, 2017
Current researches concerning network rumor control strategy mainly focus on the effect of high connectivity on information propagation,namely,the number of neighbor nodes,and pay less attention to the indirect effects induced by neighbor information ...
DIAO Jieting,FU Xiufen
doaj   +1 more source

Identifying influential spreaders in complex networks for disease spread and control

Scientific Reports, 2022
Identifying influential spreaders is an important task in controlling the spread of information and epidemic diseases in complex networks. Many recent studies have indicated that the identification of influential spreaders is dependent on the spreading ...
Xiang Wei, Junchan Zhao, Shuai Liu, Yisi Wang   +3 more
doaj   +1 more source

Comparison of blood and lymph node cells after intramuscular injection with HIV envelope immunogens

Frontiers in Immunology, 2022
BackgroundHarnessing CD4+ T cell help in the lymph nodes through rational antigen design could enhance formation of broadly neutralizing antibodies (bNAbs) during experimental HIV immunization.
Suzanne Day, Charandeep Kaur, Hannah M. Cheeseman, Emily de Groot, Emily de Groot, Leon R. McFarlane, Maniola Tanaka, Sofia Coelho, Tom Cole, Nana-Marie Lemm, Nana-Marie Lemm, Adrian Lim, Rogier W. Sanders, Rogier W. Sanders, Rogier W. Sanders, Becca Asquith, Robin J. Shattock, Katrina M. Pollock, Katrina M. Pollock   +18 more
doaj   +1 more source

Immunization strategies for simplicial irreversible epidemic on simplicial complex

Frontiers in Physics, 2022
Higher-order networks can be used to describe the interaction of multiple entities in real-world collective behaviors such as dining, conference attendance, and public transportation use.
Wenjie Li, Linghao Ni, Yue Zhang, Sheng Su, Sheng Su, Bin Peng, Wei Wang   +6 more
doaj   +1 more source

Mycobacteria-Specific T Cells Are Generated in the Lung During Mucosal BCG Immunization or Infection With Mycobacterium tuberculosis

Frontiers in Immunology, 2020
Specific T cell responses are central for protection against infection with M. tuberculosis. Here we show that mycobacteria-specific CD4 and CD8 T cells accumulated in the lung but not in the mediastinal lymph node (MLN) at different time points after M.
Juan I. Basile, Ruining Liu, Wenjun Mou, Yu Gao, Berit Carow, Martin E. Rottenberg   +5 more
doaj   +1 more source