Results 11 to 20 of about 51,241 (256)

Plant immunity: the EDS1 regulatory node [PDF]

open access: yesCurrent Opinion in Plant Biology, 2005
ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) and its interacting partner, PHYTOALEXIN DEFICIENT 4 (PAD4), constitute a regulatory hub that is essential for basal resistance to invasive biotrophic and hemi-biotrophic pathogens. EDS1 and PAD4 are also recruited by Toll-Interleukin-1 receptor (TIR)-type nucleotide binding-leucine rich repeat (NB-LRR) proteins
Wiermer, M., Feys, B., Parker, J.
openaire   +3 more sources

Evaluation of the Sentinel Immunized Node for Immune Monitoring of Cancer Vaccines [PDF]

open access: yesAnnals of Surgical Oncology, 2008
We hypothesized that lymph nodes draining sites of cutaneous vaccination could be identified by sentinel node biopsy techniques, and that measuring T-cell response with lymphocytes obtained from these lymph nodes would provide a more sensitive measure of immunogenicity than would the same measurement made with peripheral blood lymphocytes (PBL).ELISpot
Craig L, Slingluff   +12 more
openaire   +2 more sources

Lymph Node Immune Profiles as Predictive Biomarkers for Immune Checkpoint Inhibitor Response [PDF]

open access: yesFrontiers in Molecular Biosciences, 2021
The need for predictive biomarkers that can accurately predict patients who will respond to immune checkpoint inhibitor (ICI) immunotherapies remains a clinically unmet need. The majority of research efforts have focused on expression of immune-related markers on the tumour and its associated tumour microenvironment (TME).
Emily F. Goode   +4 more
openaire   +4 more sources

Node Immunization with Non-backtracking Eigenvalues

open access: yesCoRR, 2020
The non-backtracking matrix and its eigenvalues have many applications in network science and graph mining, such as node and edge centrality, community detection, length spectrum theory, graph distance, and epidemic and percolation thresholds. Moreover, in network epidemiology, the reciprocal of the largest eigenvalue of the non-backtracking matrix is ...
Leo Torres 0003   +3 more
openaire   +2 more sources

IFNγ is a central node of cancer immune equilibrium

open access: yesCell Reports, 2023
Tumors in immune equilibrium are held in balance between outgrowth and destruction by the immune system. The equilibrium phase defines the duration of clinical remission and stable disease, and escape from equilibrium remains a major clinical problem.
Michael J. Walsh   +7 more
openaire   +3 more sources

Mesenteric lymph nodes at the center of immune anatomy [PDF]

open access: yesThe Journal of Experimental Medicine, 2006
The surface of the intestinal mucosa is constantly assaulted by food antigens and enormous numbers of commensal microbes and their products, which are sampled by dendritic cells (DCs). Recent work shows that the mesenteric lymph nodes (MLNs) are the key site for tolerance induction to food proteins and that they also act as a firewall to prevent live ...
Macpherson, Andrew J., Smith, Karen
openaire   +2 more sources

Growth and Immune Evasion of Lymph Node Metastasis [PDF]

open access: yesFrontiers in Oncology, 2018
Cancer patients with lymph node (LN) metastases have a worse prognosis than those without nodal disease. However, why LN metastases correlate with reduced patient survival is poorly understood. Recent findings provide insight into mechanisms underlying tumor growth in LNs.
Dennis Jones   +5 more
openaire   +5 more sources

Avalanche-size distribution of Cayley tree

open access: yesScientific Reports, 2023
Attacks on networks is a very important issue in developing strategies of eradicating spreads of malicious phenomena in networks, such as epidemics and fake information. This field of research is referred to as networks immunization.
Amikam Patron
doaj   +1 more source

Effective Graph Protection Method to Prevent the Spreading of Attacks in Networks

open access: yesIndonesian Journal of Computing, Engineering and Design, 2019
Networks are fundamental models for representing and analyzing the structures of real-world systems. For instance, in social networks, nodes are used to represent users and edges represent the connection between users.
A. W. Wijayanto, A. Pindarwati
doaj   +1 more source

Dynamics-Preserving Graph Embedding for Community Mining and Network Immunization

open access: yesInformation, 2020
In recent years, the graph embedding approach has drawn a lot of attention in the field of network representation and analytics, the purpose of which is to automatically encode network elements into a low-dimensional vector space by preserving certain ...
Jianan Zhong, Hongjun Qiu, Benyun Shi
doaj   +1 more source

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