Results 41 to 50 of about 51,241 (256)

Lung cDC1 and cDC2 dendritic cells priming naive CD8+ T cells in situ prior to migration to draining lymph nodes

open access: yesCell Reports, 2023
Summary: The current paradigm indicates that naive T cells are primed in secondary lymphoid organs. Here, we present evidence that intranasal administration of peptide antigens appended to nanofibers primes naive CD8+ T cells in the lung independently ...
Youhui Si   +9 more
doaj   +1 more source

Efficient Immunization Strategies for Computer Networks and Populations

open access: yes, 2003
We present an effective immunization strategy for computer networks and populations with broad and, in particular, scale-free degree distributions. The proposed strategy, acquaintance immunization, calls for the immunization of random acquaintances of ...
Daniel ben-Avraham   +6 more
core   +1 more source

Modelling of the node immunity change process in a network system [PDF]

open access: yesWIT Transactions on Information and Communication, 2008
In this paper we analyze the additive hazard distribution modelling in the network system with non-constant nodes’ immunities. Nodes’ immunities depend on number of cycle and unknown parameter that is defined as random variable. Bayesian approach is applied for the updating of the estimate of this random variable. In this study we are interested in how
Benas Jokšas   +2 more
openaire   +3 more sources

Immunization of networks with community structure

open access: yes, 2009
In this study, an efficient method to immunize modular networks (i.e., networks with community structure) is proposed. The immunization of networks aims at fragmenting networks into small parts with a small number of removed nodes.
  +12 more
core   +2 more sources

Neutrophil recruitment to lymph nodes limits local humoral response to Staphylococcus aureus. [PDF]

open access: yesPLoS Pathogens, 2015
Neutrophils form the first line of host defense against bacterial pathogens. They are rapidly mobilized to sites of infection where they help marshal host defenses and remove bacteria by phagocytosis.
Olena Kamenyeva   +9 more
doaj   +1 more source

Fragmenting networks by targeting collective influencers at a mesoscopic level [PDF]

open access: yes, 2016
A practical approach to protecting networks against epidemic processes such as spreading of infectious diseases, malware, and harmful viral information is to remove some influential nodes beforehand to fragment the network into small components.
Kobayashi, Teruyoshi, Masuda, Naoki
core   +3 more sources

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation [PDF]

open access: yes, 2014
Autoimmune diseases are driven by immune cells that recognize self-tissues. A major goal for treatment strategies for autoimmune diseases is to turn off or tolerize self-reactive immune cells such as CD4 T cells that coordinate tissue damage in many ...
A. David   +38 more
core   +1 more source

Analysis of Two-Worm Interaction Model in Heterogeneous M2M Network

open access: yesInformation, 2015
With the rapid development of M2M (Machine-to-Machine) networks, the damages caused by malicious worms are getting more and more serious. By considering the influences of the network heterogeneity on worm spreading, we are the first to study the complex ...
Jinhua Ma   +3 more
doaj   +1 more source

A novel role for lipoxin A4 in driving a lymph node–eye axis that controls autoimmunity to the neuroretina

open access: yeseLife, 2020
The eicosanoid lipoxin A4 (LXA4) has emerging roles in lymphocyte-driven diseases. We identified reduced LXA4 levels in posterior segment uveitis patients and investigated the role of LXA4 in the pathogenesis of experimental autoimmune uveitis (EAU ...
Jessica Wei   +7 more
doaj   +1 more source

Maternal schistosomiasis impairs offspring Interleukin-4 production and B cell expansion.

open access: yesPLoS Pathogens, 2021
Epidemiological studies have identified a correlation between maternal helminth infections and reduced immunity to some early childhood vaccinations, but the cellular basis for this is poorly understood.
Diana Cortés-Selva   +6 more
doaj   +1 more source

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