Results 121 to 130 of about 2,805,373 (250)

View-GFN: A Novel View-Based Graph Convolution and Sampling Fusion Network for 3D Shape Recognition

Applied Sciences
Three-dimensional (3D) shape recognition is a fundamental task in computer vision, where view-based methods have recently achieved state-of-the-art performance.
Min Pang, Jichao Jiao, Yingjian Zhang
doaj   +1 more source

Efficiently Approximating Top- $k$ Sequential Patterns in Transactional Graphs

IEEE Access, 2019
In real-world networks, an edge (or vertex) may be associated with a transaction database, where each transaction consists of a set of items to describe the attributes or behaviors of the edge (or vertex).
Mingtao Lei, Xi Zhang, Jincui Yang, Binxing Fang   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Research on Urban Road Traffic Flow Prediction Based on Sa-Dynamic Graph Convolutional Neural Network

Mathematics
Neural network models based on GNNs often achieve good results in traffic flow prediction tasks of traffic networks. However, most existing GNN-based methods apply a fixed graph structure to capture spatial dependencies between nodes, and fixed graph ...
Song Hu, Jian Gu, Shun Li
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Dynamic Sensor Placement Based on Sampling Theory for Graph Signals

IEEE Open Journal of Signal Processing
In this paper, we consider a sensor placement problem where sensors can move within a network over time. Sensor placement problem aims to select $K$ sensor positions from $N$ candidates where $K < N$. Most existing methods assume that sensor positions
Saki Nomura, Junya Hara, Hiroshi Higashi, Yuichi Tanaka   +3 more
doaj   +1 more source

Graph sampling for subgraph counting on directed graphs

, 2022
Die Anzahl der Teilgraphen in einem größeren Netzwerk zu berechnen ist eine wichtige Aufgabe in der Graphanalyse mit verschiedenen Anwendungsbereichen. Viele analytische Methoden, beispielsweise das Suchen nach Netzwerk Motifs, basieren auf dem Problem des Teilgraphzählens. Eine exakte Zählung ist für solche analytische Methoden oft nicht notwendig und
openaire   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source