Results 101 to 110 of about 5,227 (304)
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
This study investigates the impact of graphic novels The Bad Doctor and The Lady Doctor by Ian Williams on reader engagement, empathy, and emotional response. Utilizing a structured questionnaire distributed among a sample of English literature students,
Garret Raja, Nisha Anil Salunkhe
doaj +1 more source
Librarians' Attitudes and Perspectives Regarding Graphic Novels
Historically, graphic novels have held a precarious place in public library collections. In the past, public libraries were envisioned as institutions for education and moral improvement, and library materials were required to prove their quality ...
Horner, Emily C.
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Graphic Novel Adaptations And The Crisis Of The Ideal Reader: A Reception Theory Analysis
Graphic novel adaptations of canonical literary works challenge fundamental assumptions within contemporary reception theory, particularly the privileged status of the ideal reader construct. This paper examines how graphic novels expose the limitations
Hichem Souhali
doaj
Nonfiction graphic novels in public libraries
The purpose of this Bachelor's thesis is to study the reasoning behind classification, cataloging and shelf arrangement of nonfiction graphic novels in public libraries.
Coccomo, Jennifer, Sandberg, Josefin
core
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Gut erzählte Hochschullehre – Visuelles Storytelling mit Hilfe von Graphic Novels
Lehren und Lernen an Hochschulen verändern sich stetig. Im Zuge dessen wird häufig nach innovativen Ansätzen zur Gestaltung von Lehrveranstaltungen und Lernmaterialien gesucht.
Anja Rogas
doaj +1 more source

