Results 101 to 110 of about 5,227 (304)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Emotion through Narration: Exploring Narrative Empathy in Ian Williams’ The Bad Doctor and The Lady Doctor

open access: yesILN Journal: Indian Literary Narratives
This study investigates the impact of graphic novels The Bad Doctor and The Lady Doctor by Ian Williams on reader engagement, empathy, and emotional response. Utilizing a structured questionnaire distributed among a sample of English literature students,
Garret Raja, Nisha Anil Salunkhe
doaj   +1 more source

Librarians' Attitudes and Perspectives Regarding Graphic Novels

open access: yes, 2006
Historically, graphic novels have held a precarious place in public library collections. In the past, public libraries were envisioned as institutions for education and moral improvement, and library materials were required to prove their quality ...
Horner, Emily C.
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Graphic Novel Adaptations And The Crisis Of The Ideal Reader: A Reception Theory Analysis

open access: yesThe Journal of Studies in Language, Culture and Society
Graphic novel adaptations of canonical literary works challenge fundamental assumptions within contemporary reception theory, particularly the privileged status of the ideal reader construct. This paper examines how graphic novels expose the limitations
Hichem Souhali
doaj  

Nonfiction graphic novels in public libraries

open access: yes, 2014
The purpose of this Bachelor's thesis is to study the reasoning behind classification, cataloging and shelf arrangement of nonfiction graphic novels in public libraries.
Coccomo, Jennifer, Sandberg, Josefin
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Gut erzählte Hochschullehre – Visuelles Storytelling mit Hilfe von Graphic Novels

open access: yesZeitschrift für Hochschulentwicklung
Lehren und Lernen an Hochschulen verändern sich stetig. Im Zuge dessen wird häufig nach innovativen Ansätzen zur Gestaltung von Lehrveranstaltungen und Lernmaterialien gesucht.
Anja Rogas
doaj   +1 more source

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