Results 121 to 130 of about 5,227 (304)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Teaching Literary Theory through Annotated Graphic Novels
, 2017 Three original works are presented to demonstrate how Graphic Novels can be used to introduce students to critical works as well as literary texts. It has been well established that Graphic Novels are an effective format for introducing students to ...
Thompson, Kathryn B, Miss
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Revitalizing Tier 2 Intervention with Graphic Novels
, 2012 The authors explore the practice of incorporating graphic novels in a Tier 2 Response To Intervention (RTI) program for five elementary-aged struggling readers in an urban school.
Grisham, Dana L., Smetana, Linda
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Daddy issues in graphic novels
, 2021 This paper is based on an interdisciplinary academic issue. The first part is concerning literary analysis of selected graphic novels, while the second part addresses the didactic opportunities and difficulties involved in teaching in the genre, and how ...
Mundus, Frederikke +2 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Narrative medicine pinpoints loss of autonomy and stigma in Parkinson's disease. [PDF]
NPJ Parkinsons Dis, 2023 Florijn BW +3 more
europepmc +1 more source
Student engagement within the use of graphic novels
, 2019 Student engagement in novels is a key factor in whether or not a student can be successful in reading. The purpose of this study was to analyze student engagement with graphic novels and traditional novels, and to describe any preferences students had ...
Felsenthal, Melissa
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source