Results 91 to 100 of about 48,970 (328)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Visual Inference and Graphical Representation in Regression Discontinuity Designs
, 2022 Christina Korting +4 more
openalex +1 more source
An Enumeration of Graphical Designs
, 2006 : Let (t, k) denote the set of pairs (v, λ) for which there exists a graphical t-(v, k, λ) design. Most results on graphical designs have gone to show the finiteness of (t, k) when t and k satisfy certain conditions.
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A multi-national, multi-institutional study of student-generated software designs [PDF]
, 2004 This paper reports a multi-national, multi-institutional study to investigate Computer Science students ’ understanding of software design and software design criteria.
Bouvier, Dennis +10 more
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Calculating and graphing within-subject confidence intervals for ANOVA
, 2011 The psychological and statistical literature contains several proposals for calculating and plotting confidence intervals for within-subject (repeated measures) ANOVA designs.
Thom Baguley, Baguley, T
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
, 1997 A fundamental question in the theory of combinatorial designs is to ask what designs can be obtained with a particular automorphism group. This work completely determines all proper Steiner graphical t-wise balanced designs that have the group $S\sb{n ...
Olsen, Cheryl L
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interfaz Gráfica Computacional para Destilación Multicomponente utilizando Métodos Cortos
Nexo, 2011 En este trabajo, se elaboró una interfaz gráfica que determina por medio de simulación en estado estacionario el número de platos necesarios en el proceso de destilación multicomponente, así como la composición en el flujo de destilado y fondos de una ...
A. Osorio Mirón +1 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source