Results 71 to 80 of about 48,970 (328)
BMC Genomics, 2008 Background The MIAME and MAGE-OM standards defined by the MGED society provide a specification and implementation of a software infrastructure to facilitate the submission and sharing of data from microarray studies via public repositories.
Ivens Alasdair, Qureshi Matloob
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Optimal designs for dose finding experiments in toxicity studies [PDF]
We construct optimal designs for estimating fetal malformation rate, prenatal death rate and an overall toxicity index in a toxicology study under a broad range of model assumptions.
Dette, Holger +2 more
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Graphical techniques for the assessment of Bayesian optimal designs
, 2022 Response surface methodology is a well-developed paradigm of statistical design and analysis that involves design of experiments, collection of data, conduction of regression analysis and evaluation of the fitted relationship between the factors and ...
Ahmed, Nasiba Maruf
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Belt-Driven Open Source Circuit Mill Using Low-Cost 3-D Printer Components
Inventions, 2018 Barriers to inventing electronic devices involve challenges of iterating electronic designs due to long lead times for professional circuit board milling or high costs of commercial milling machines.
Shane Oberloier, Joshua M. Pearce
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
An improved finiteness theorem for graphical t-designs
, 2001 We prove that there exist only finitely many nontrivial graphical t-(v,k,λ) designs when k≤4t/3. This improves a previous result of Betten et al. (Discrete Math. 197/198 (1999) 83–109)
Yeow Meng Chee, Chee, Yeow Meng
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2007 Grafiksel t-tasarımları, kombinatöryel tasarımlar sınıfına girer ve tasarım teorisinin en önemli yapılarıdır. Bu tasarımlar istatistiksel deneylerde yapı maliyetlerini minimum yapmada önemlidir.
KARABACAK, AYLİN
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