Results 91 to 100 of about 22,868,572 (367)

Context-specific independencies for ordinal variables in chain regression models [PDF]

open access: yes, 2017
In this work we handle with categorical (ordinal) variables and we focus on the (in)dependence relationship under the marginal, conditional and context-specific perspective.
Cazzaro, Manuela, Nicolussi, Federica
core   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Probabilistic Community Using Link and Content for Social Networks

open access: yesIEEE Access, 2017
Community detection is one of the most important problems in social network analysis in the context of the structure of underlying graphs. Many researchers have proposed methods, which only consider the network structure of social networks, for ...
Shuai Zhao, Le Yu, Bo Cheng
doaj   +1 more source

Stratified Gaussian graphical models [PDF]

open access: yesCommunications in Statistics - Theory and Methods, 2016
23 pages, 12 ...
Nyman, Henrik   +2 more
openaire   +4 more sources

Graphical tools for model-based mixture discriminant analysis

open access: yes, 2013
The paper introduces a methodology for visualizing on a dimension reduced subspace the classification structure and the geometric characteristics induced by an estimated Gaussian mixture model for discriminant analysis.
Scrucca, Luca
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Efficient Proximal Gradient Algorithms for Joint Graphical Lasso

open access: yesEntropy, 2021
We consider learning as an undirected graphical model from sparse data. While several efficient algorithms have been proposed for graphical lasso (GL), the alternating direction method of multipliers (ADMM) is the main approach taken concerning joint ...
Jie Chen, Ryosuke Shimmura, Joe Suzuki
doaj   +1 more source

Maximum likelihood thresholds of Gaussian graphical models and graphical lasso [PDF]

open access: yesarXiv, 2023
Associated to each graph G is a Gaussian graphical model. Such models are often used in high-dimensional settings, i.e. where there are relatively few data points compared to the number of variables. The maximum likelihood threshold of a graph is the minimum number of data points required to fit the corresponding graphical model using maximum ...
arxiv  

Graphical LASSO Based Model Selection for Time Series

open access: yes, 2014
We propose a novel graphical model selection (GMS) scheme for high-dimensional stationary time series or discrete time process. The method is based on a natural generalization of the graphical LASSO (gLASSO), introduced originally for GMS based on i.i.d.
Görtz, Norbert   +2 more
core   +2 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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