Results 91 to 100 of about 355,655 (334)

Жизнь ясновидца упадка. Введение в творческую биографию Альфреда Кубина

open access: yesИскусство Евразии, 2016
Статья посвящена биографии малоизученного в России австрийского художника, иллюстратора и писателя Альфреда Кубина. Художник был участником таких творческих объединений, как «Новое мюнхенское художественное объединение» и «Синий всадник».
Кушнарева, А.В.
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

THE ANALISYS OF NARRATIVE AND SYMBOLIC STRUCTURES IN BOOK GRAPHICS IN THE MOLDOVAN SOVIET SOCIALIST REPUBLIC IN THE PERIOD OF SOCIALIST REALISM (1945-1953) [PDF]

open access: yesStudiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2016
In the process of transition to socialist realism, the fine art of the ‘40s, including graphics, was characterized by documentalism and illustrativism in various thematic approaches to everyday life.
ROCACIUC VICTORIA
doaj  

Design of a time-sharing system allowing interactive graphics [PDF]

open access: bronze, 1968
G. B. Anderson   +5 more
openalex   +1 more source

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