Results 61 to 70 of about 1,216,906 (379)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Teaching and Learning Data Visualization: Ideas and Assignments

open access: yes, 2015
This article discusses how to make statistical graphics a more prominent element of the undergraduate statistics curricula. The focus is on several different types of assignments that exemplify how to incorporate graphics into a course in a pedagogically
Nolan, Deborah, Perrett, Jamis
core   +2 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Личность художника в зеркале творчества

open access: yesИскусство Евразии, 2020
В статье сделан обзор выставки Михаил Верхоланцев. Ксилографии в Ирбитском государственном музее изобразительных искусств. В составе ретроспективной экспозиции 132 гравюры, созданные в период с 1970 по 2018 год.
Оськина, Ирина Николаевна
doaj   +1 more source

A SERVICE-ORIENTED INDOOR POINT CLOUD PROCESSING PIPELINE [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Visualization of point clouds plays an important role in understanding the context of the digital representation of the built environment. Modern commodity mobile devices (e.g., smartphones and tablets), are capable of capturing representations in the ...
V. Stojanovic   +3 more
doaj   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Fundamentals of computer graphics

open access: yes, 2018
The broad acceptance and use of this book as one of the leading introductory computer graphics texts has enabled the original author and coauthors to update the chapters and contribute new material involving the most knowledgeable experts in different ...
P. Shirley
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

plotROC: A Tool for Plotting ROC Curves

open access: yesJournal of Statistical Software, 2017
Plots of the receiver operating characteristic (ROC) curve are ubiquitous in medical research. Designed to simultaneously display the operating characteristics at every possible value of a continuous diagnostic test, ROC curves are used in oncology to ...
Michael C. Sachs
doaj   +1 more source

Approximate Bayesian Image Interpretation using Generative Probabilistic Graphics Programs [PDF]

open access: yes, 2013
The idea of computer vision as the Bayesian inverse problem to computer graphics has a long history and an appealing elegance, but it has proved difficult to directly implement.
Kulkarni, Tejas D.   +3 more
core   +4 more sources

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