Results 81 to 90 of about 3,335,840 (376)

A knowledge based software engineering environment testbed [PDF]

open access: yes, 1985
The Carnegie Group Incorporated and Boeing Computer Services Company are developing a testbed which will provide a framework for integrating conventional software engineering tools with Artifical Intelligence (AI) tools to promote automation and ...
Baker, L., Gill, C., Reedy, A.
core   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Graphics software tool for VT terminals (VTGRAPH) [PDF]

open access: yes
VTGRAPH is a graphics software tool for using DEC/VT or VT compatible terminals. It allows the user to deal with computer environments which use VT terminals for window management and graphics systems.
Wang, Caroline
core   +1 more source

GenomeGraphs: integrated genomic data visualization with R. [PDF]

open access: yes, 2009
BackgroundBiological studies involve a growing number of distinct high-throughput experiments to characterize samples of interest. There is a lack of methods to visualize these different genomic datasets in a versatile manner.
Bullard, James   +3 more
core   +3 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

A study of real-time computer graphic display technology for aeronautical applications [PDF]

open access: yes
Hardware, algorithms and software for real-time raster graphics were designed and ...
Blume, L. R., Rajala, S. A.
core   +1 more source

BrainPainter: A software for the visualisation of brain structures, biomarkers and associated pathological processes [PDF]

open access: yes, 2019
We present BrainPainter, a software that automatically generates images of highlighted brain structures given a list of numbers corresponding to the output colours of each region. Compared to existing visualisation software (i.e.
Alexander, Daniel C.   +3 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Real-time graphics for the Space Station Freedom cupola, developed in the Systems Engineering Simulator [PDF]

open access: yes
Among the Lyndon B. Johnson Space Center's responsibilities for Space Station Freedom is the cupola. Attached to the resource node, the cupola is a windowed structure that will serve as the space station's secondary control center.
Hess, Philip W., Red, Michael T.
core   +1 more source

Increasing trap stiffness with position clamping in holographic optical tweezers [PDF]

open access: yes, 2009
We present a holographic optical tweezers system capable of position clamping multiple particles. Moving an optical trap in response to the trapped object's motion is a powerful technique for optical control and force measurement.
Bowman, R.   +5 more
core   +1 more source

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