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Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is the most common cause of hyperthyroidism and occurs at all ages but especially in women of reproductive age. Graves' hyperthyroidism is caused by autoantibodies to the thyroid-stimulating hormone receptor (TSHR) that act as agonists and induce excessive ...
Davies, Terry F. +8 more
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Thyroid function disorders [PDF]
Thyroid function disorders are the most common endocrine disorders in humans. They are frequently diagnosed, with prevalence varying between 2 and 6%, and a female to male ratio of up to 10:1.
Stojković Mirjana
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Background: Graves' disease is responsible for 60-80% causes of hyperthyreosis. An important role in the pathogenesis is played by anti-TSHR immunoglobulins (TRAb), that stimulate TSH receptors leading to excessive hormone synthesis and release by the ...
Natalia Woś +9 more
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Evans syndrome and Graves' Disease: An unusual presentation – A case report
Introduction: Evans syndrome (ES), an infrequently encountered haematological condition, is characterized by coombs-positive autoimmune hemolytic anaemia (AIHA) in association with immune thrombocytopenia (ITP). The association of ES with Graves' disease
Amtoj Singh Lamba +3 more
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Graves' disease is an autoimmune thyroid disease with several characteristic symptoms and signs. Graves' ophthalmopathy, an inflammatory disease in the orbital area, is the main extrathyroid manifestation of Graves' disease.
Herry Krisnata Ginting, Soebagijo Adi
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Graves-Basedow disease and potential risk factors [PDF]
Background/Aim. Graves-Basedow disease is a common multifactorial genetic syndrome, which is determined by several genes and environmental factors. The aim of the present study was to investigate the presence of risk factors for developing Graves-Basedow
Živanović Dušica +3 more
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Pretibial myxedema: Paradoxical manifestation of thyroid dermopathy after I-131 ablation therapy
Pretibial myxedema (PM) is an unusual extrathyroidal manifestation of Graves' disease (GD), which affects approximately 1%–5% of the patients. In addition, PM usually occurs in the hyperthyroid state of GD, and the high level of thyroid autoantibodies is
Bing-Sian Lin +2 more
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Case series of dermopathy in autoimmune thyroid disease [PDF]
Graves' disease (GD) is an autoimmune disease that can affect other tissues in addition to the thyroid gland. The clinical manifestations are a result of the impact of TSH receptor antibodies.
Janić Tamara +8 more
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The role of apoptosis in development of autoimmune thyroid diseases
In the review representations about a role apoptosis by autoimmune thyroid diseases, such as Graves' disease and Hashimoto's thyroiditis, the basic pathogenetic links immunological abnormalities at the these diseases have been discussed.
Yu. V. Nedosekova +3 more
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Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto +4 more
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