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Nature Reviews Disease Primers, 2020 Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is the most common cause of hyperthyroidism and occurs at all ages but especially in women of reproductive age. Graves' hyperthyroidism is caused by autoantibodies to the thyroid-stimulating hormone receptor (TSHR) that act as agonists and induce excessive ...
Davies, Terry F. +8 more
semanticscholar +9 more sources
Radioiodine treatment for graves’ disease: a 10-year Australian cohort study
BMC Endocrine Disorders, 2018 Background Radioactive iodine (I131) is a common definitive treatment for Graves’ Disease. Potential complications include worsening, or new development of Graves’ eye disease and development of a radiation thyroiditis.
Erin Fanning +2 more
doaj +2 more sources
Microchimerism in Graves' Disease [PDF]
Journal of Thyroid Research, 2012 Microchimerism is the presence of cells from one individual in another genetically distinct individual. Pregnancy is the main cause of natural microchimerism through transplacental bidirectional cell trafficking between mother and fetus. The consequences of pregnancy-related microchimerism are under active investigation.
Galofre, J.C. (Juan Carlos)
openaire +7 more sources
New England Journal of Medicine, 2016 Smith, Terry J, Hegedüs, Laszlo
semanticscholar +13 more sources
Epidemiology, management and outcomes of Graves’ disease—real life data [PDF]
Endocrine, 2017 PurposeTreatment options in Graves’ disease are clearly defined, but management practices and the perceptions of success are varied. The outcomes of treatment in large consecutive cohorts of Graves’ disease have not been well characterised.
Y. Hussain +3 more
semanticscholar +3 more sources
The Journal of Clinical Endocrinology & Metabolism, 2007 Rebecca, Bahn +2 more
semanticscholar +5 more sources
Current and Future Treatments for Graves’ Disease and Graves’ Ophthalmopathy [PDF]
Hormone and Metabolic Research, 2018 The course and pathogenesis of Graves’ disease and Graves’ ophthalmopathy are interdependent, influencing each other’s therapeutic choices. Multiple factors including geographic location, access to medical services, patient and physician preferences ...
Anupam Kotwal, Marius N. Stan
openalex +2 more sources
Thyroid function disorders [PDF]
Arhiv za farmaciju, 2022 Thyroid function disorders are the most common endocrine disorders in humans. They are frequently diagnosed, with prevalence varying between 2 and 6%, and a female to male ratio of up to 10:1.
Stojković Mirjana
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Journal of Education, Health and Sport, 2023 Background: Graves' disease is responsible for 60-80% causes of hyperthyreosis. An important role in the pathogenesis is played by anti-TSHR immunoglobulins (TRAb), that stimulate TSH receptors leading to excessive hormone synthesis and release by the ...
Natalia Woś +9 more
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The genetics of Graves’ disease
Reviews in Endocrine & Metabolic Disorders, 2023 Graves’ disease (GD) is the commonest cause of hyperthyroidism and has a strong female preponderance. Everyday clinical practice suggests strong aggregation within families and twin studies demonstrate that genetic factors account for 60-80% of risk of ...
Lydia Grixti, L. Lane, S. Pearce
semanticscholar +1 more source