Results 51 to 60 of about 9,264,457 (358)
Risk factors for thyroid-associated orbitopathy due to Graves' disease
Journal of Clinical Ophthalmology and Research, 2021 Background: Thyroid-associated orbitopathy (TAO) is the principal extrathyroidal manifestation of Graves' disease (GD). TAO is described as chronic inflammation of orbital and periorbital tissue.
Tauseef Nabi +2 more
doaj +1 more source
Glycosuria and graves’s disease [PDF]
The Dublin Journal of Medical Science, 1910 n ...
openaire +3 more sources
Epidemiology, management and outcomes of Graves’ disease—real life data
Endocrine, 2017 PurposeTreatment options in Graves’ disease are clearly defined, but management practices and the perceptions of success are varied. The outcomes of treatment in large consecutive cohorts of Graves’ disease have not been well characterised.
Y. Hussain +3 more
semanticscholar +1 more source
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Graves' Disease: Can It Be Cured?
Endocrinology and Metabolism, 2019 Whether or not Graves' hyperthyroidism can be really cured, depends on the definition of “cure.” If eradication of thyroid hormone excess suffices for the label “cure,” then all patients can be cured because total thyroidectomy or high doses of 131I will
W. Wiersinga
semanticscholar +1 more source
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Клиническая и экспериментальная тиреоидология, 2011 The aim of the study was to estimate a level of thyrotropin-receptor antibodies (TRAb), some cytokines (TNF-α, IL-8, IL-10) in Graves' disease patients with chronic heart failure (CHF) and to reveal prognostic factors of CHF.89 patients with Graves ...
doaj +1 more source
Biotin Treatment Mimicking Graves' Disease.
New England Journal of Medicine, 2016 In six children, biotin produced changes in thyroid-function tests that mimic those seen in Graves' disease.
S. Kummer, D. Hermsen, F. Distelmaier
semanticscholar +1 more source