Results 21 to 30 of about 225,386 (188)
Quantitative MRI Assessment of Orbital Structures in Radioactive Iodine-131 Therapy for Inactive Graves' Ophthalmopathy. [PDF]
Int J EndocrinolObjective The understanding regarding the role of orbital magnetic resonance imaging (MRI) in predicting the prognosis of radioactive iodine‐131 (I‐131) therapy for patients with inactive Graves’ ophthalmopathy (GO) is limited. Therefore, this study aimed to explore the application of MRI quantitative measurements of orbital structures in radioactive I‐
Wang M, Shen ZY, Wu XW.
europepmc +2 more sources
TSHR-Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition. [PDF]
Adv Sci (Weinh)This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Zhang Y +16 more
europepmc +2 more sources
Clinical Ophthalmology, 2012 Tom McCorquodale,1 Hooshang Lahooti,1 Bamini Gopinath,2 Jack R Wall11Department of Medicine, Nepean Clinical School, the University of Sydney, Penrith, NSW, Australia; 2Centre for Vision Research, the University of Sydney, Westmead Hospital, Westmead ...
McCorquodale T +3 more
doaj +1 more source
A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]
, 1994 Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Sarkar, Gobinda +4 more
core +1 more source
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
, 1996 To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Wenzel, Björn E. +2 more
core +1 more source
The thickness of the retrobulbar portion of the optic nerve in Graves ophthalmopathy measured by ultrasound [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 Introduction. The clinical diagnostic of Graves ophthalmopathy is based on the association of ocular signs and the disease of the thyroid gland. The evolution of the disease involves the development of eye globe protrusion, extraocular muscle thickening ...
Stefanović Ivan +3 more
doaj +1 more source
Revista Brasileira de Oftalmologia, 2009 Relatam-se dois casos clínicos de prolapso de gordura orbitária, sendo um associado à oftalmopatia de Graves. Os pacientes apresentavam em comum exame clínico com elevação na região temporal da órbita direita e aumento da gordura intraorbitária na ...
Kim-Ir-Sen Santos Teixeira +4 more
doaj +1 more source
Preventing Graves' Ophthalmopathy [PDF]
New England Journal of Medicine, 1998 Graves' ophthalmopathy and Graves' hyperthyroidism are closely linked, but the precise relation between these different expressions of the same disease is poorly understood.
openaire +3 more sources
BMC Ophthalmology, 2019 Background To demonstrate that the Corvis ST could be used to quantify the biomechanical parameters of the orbital soft tissues by measuring and comparing whole eye movement (WEM) using the Corvis in normal eyes and in eyes of patients with Graves ...
Ho Sik Hwang +3 more
doaj +1 more source
Journal of Ophthalmology, 2020 Purpose. We aimed to evaluate foveal and parafoveal density using optical coherence tomography angiography and the alteration on the retinal vessel diameter in patients with inactive Graves’ ophthalmopathy compared to age-matched normal population ...
Cetin Akpolat +4 more
doaj +1 more source