Results 31 to 40 of about 224,706 (187)

Efficacy and safety of three different cumulative doses of intravenous methylprednisolone for moderate to severe and active Graves' orbitopathy [PDF]

, 2012
BACKGROUND: Optimal doses of i.v. glucocorticoids for Graves' orbitopathy (GO) are undefined. METHODS: We carried out a multicenter, randomized, double-blind trial to determine efficacy and safety of three doses of i.v. methylprednisolone in 159 patients
Bernard M, for the European Group on Graves' Orbitopathy, Soeters, M R, Daumerie, C., Currò N, Nardi, M, Mourits, M P, Salvi M, Stahl, M., Boboridis KG, Nardi, M., Bernard, M., Stahl, M, Daumerie C, Baldeschi, L., Azzolini, C, Wiersinga, W., Sassi, L, Boschi A, MARCOCCI, CLAUDIO, Currò, N, Wiersinga W, von Arx, G, Boschi, A., Bournaud C, Boboridis, K G, Veronesi, G., Stahl M, Bartalena L, BALDESCHI, LELIO, Veronesi, G, Baldeschi, L, Bournaud, C., Mourits, M. P., Krassas GE, Sassi, L., Salvi, M., Currò, N., Krassas G, Baldeschi L, Veronesi G, Boschi, Antonella, VERONESI, GIOVANNI, Marcocci, C, SASSI, LORENZA, Azzolini C, Azzolini, C., von Arx, G., Mourits MP, Nardi M, Wiersinga, W, AZZOLINI, CLAUDIO, NARDI, MARCO, Bernard, M, for the European Group on Graves Orbitopathy, Boboridis, K. G., von Arx G, European Group on Graves' Orbitopathy, Marcocci C, Krassas, G. E., Daumerie, Chantal, Wiersinga WM, Soeters, M. R., Marcocci, C., BARTALENA, LUIGI, Bournaud, C, Salvi, M, Soeters MR, Sassi L, Curr? N, Bartalena, L., Krassas, G E, Bartalena, L   +72 more
core   +1 more source

Medical Treatment of Graves’ Orbitopathy

Hormone and Metabolic Research, 2015
The medical treatment of Graves' orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20-30% of patients are not responsive and about 20% present with disease recurrence.
Salvi, M., Campi, I.
openaire   +2 more sources

Late recurrence of unilateral graves orbitopathy on the contralateral side

, 2002
PURPOSE: To report a case of late recurrence of unilateral Graves orbitopathy on the contralateral side after 7 years. DESIGN: Interventional case report.
Mourits, Maarten P., Maarten P. Mourits, Rachel Kalmann, Kalmann, Rachel   +3 more
core   +2 more sources

What has changed in thyroid eye disease in the last five years (2020–2025)

European Thyroid Journal
Background: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials.
Mario Salvi
doaj   +1 more source

Exophthalmos in a young woman with no Graves’ disease – a case report of IgG4-related orbitopathy

BMC Ophthalmology, 2018
Background Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy ...
Annamaria Erdei, Zita Steiber, Csaba Molnar, Ervin Berenyi, Endre V. Nagy   +4 more
doaj   +1 more source

Antioxidant Therapy in Graves’ Orbitopathy

Frontiers in Endocrinology, 2020
The balance of the cell redox state is a key point for the maintenance of cellular homeostasis. Increased reactive oxygen species (ROS) generation leads to oxidative damage of tissues, which is involved in the development of several diseases, including ...
Giulia Lanzolla, Claudio Marcocci, Michele Marinò   +2 more
doaj   +1 more source

Diagnosis of Graves’ Orbitopathy

, 2023
Abstract The diagnosis of Graves’ orbitopathy is based on a typical clinical presentation, supported by a family history of Graves’ disease, in combination with typical findings on CT or MRI scans and/or elevated serum levels of TSH-receptor-binding immunoglobulins and anti-thyroid peroxidase.
openaire   +2 more sources

Antithymocyte Globulin as Second-Line Therapy in Graves Orbitopathy—Preliminary Results From a Prospective Single-Center Study

Frontiers in Endocrinology, 2022
ObjectiveManagement of Graves’ orbitopathy remains a challenge. Our previous case report has shown promising results for rabbit antithymocyte globulin (rATG) in the treatment of Graves’ orbitopathy.DesignWe present the response of 7 individuals with ...
Monika Sarnat-Kucharczyk, Maria Świerkot, Gabriela Handzlik, Grażyna Kulawik, Krystyna Jagoda, Iga Grochoła-Małecka, Joanna Fryżewska, Ewa Mrukwa-Kominek, Jerzy Chudek   +8 more
doaj   +1 more source

Thyroid Eye Disease due to Immune Reconstitution Inflammatory Syndrome as a Consequence of Antiretroviral Therapy in the Setting of AIDS

Case Reports in Endocrinology, 2020
We describe a case of worsening Graves’ orbitopathy due to immune reconstitution inflammatory syndrome (IRIS) in a 38-year-old HIV-infected male after beginning ART (antiretroviral therapy).
Ravali Nallu, Parvathy Madhavan, Lisa Chirch, Pooja Luthra   +3 more
doaj   +1 more source

Orbital lymphoma associated with Graves’ disease: A case report [PDF]

Vojnosanitetski Pregled, 2014
Introduction. The presence of bilateral exophthalmos and palpebral, periorbital edema associated with hyperthyroidism is most often considered as an initial sign of Graves’ ophthalmopathy.
Hajduković Zoran, Kuzmić-Janković Snežana, Kljaković-Avramović Tamara, Sekulović Leposava, Tukić Ljiljana   +4 more
doaj   +1 more source