Results 31 to 40 of about 7,663 (215)

Exophthalmos in a young woman with no Graves’ disease – a case report of IgG4-related orbitopathy

open access: yesBMC Ophthalmology, 2018
Background Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy ...
Annamaria Erdei   +4 more
doaj   +1 more source

Antioxidant Therapy in Graves’ Orbitopathy

open access: yesFrontiers in Endocrinology, 2020
The balance of the cell redox state is a key point for the maintenance of cellular homeostasis. Increased reactive oxygen species (ROS) generation leads to oxidative damage of tissues, which is involved in the development of several diseases, including ...
Giulia Lanzolla   +2 more
doaj   +1 more source

Quality of life in Graves' orbitopathy [PDF]

open access: yesMedicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor", 2011
The quality of life of patients with Graves' orbitopathy (GO) may be seriously damaged due to the changes in appearance, working abilities and everyday activities. The reasons for the deterioration in quality of life in GO are proptosis, diplopiae and/or
Ćirić Jasmina
doaj   +1 more source

What has changed in thyroid eye disease in the last five years (2020–2025)

open access: yesEuropean Thyroid Journal
Background: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials.
Mario Salvi
doaj   +1 more source

Thyroid Eye Disease due to Immune Reconstitution Inflammatory Syndrome as a Consequence of Antiretroviral Therapy in the Setting of AIDS

open access: yesCase Reports in Endocrinology, 2020
We describe a case of worsening Graves’ orbitopathy due to immune reconstitution inflammatory syndrome (IRIS) in a 38-year-old HIV-infected male after beginning ART (antiretroviral therapy).
Ravali Nallu   +3 more
doaj   +1 more source

Orbital lymphoma associated with Graves’ disease: A case report [PDF]

open access: yesVojnosanitetski Pregled, 2014
Introduction. The presence of bilateral exophthalmos and palpebral, periorbital edema associated with hyperthyroidism is most often considered as an initial sign of Graves’ ophthalmopathy.
Hajduković Zoran   +4 more
doaj   +1 more source

Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]

open access: yes, 2020
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter   +7 more
core   +1 more source

Aggravated Orbitopathy Following Remnant Ablation in a Patient with Multiple Cancers

open access: yesEndocrinology Research and Practice, 2017
The rate of thyroid cancer in the patients with Graves’ disease is controversial. The rare incidents of multiple primary thyroid cancers in the same patient have been reported.
Umut MOUSA   +4 more
doaj   +1 more source

The change in the clinical presentation of Graves’ disease: a 30 years retrospective survey in an academic Brazilian tertiary center

open access: yesArchives of Endocrinology and Metabolism, 2020
Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto   +4 more
doaj   +1 more source

Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]

open access: yesHormone and Metabolic Research, 2015
AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P   +3 more
openaire   +3 more sources

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