Results 41 to 50 of about 230,574 (171)

The change in the clinical presentation of Graves’ disease: a 30 years retrospective survey in an academic Brazilian tertiary center

open access: yesArchives of Endocrinology and Metabolism, 2020
Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto   +4 more
doaj   +1 more source

Natural history of graves’ orbitopathy after treatment

open access: yes, 2016
Intravenous glucocorticoids are used for Graves’ orbitopathy, alone or associated with/followed by additional treatments (orbital radiotherapy, orbital decompression, palpebral or eye surgery).
SELLARI FRANCESCHINI, STEFANO   +9 more
core   +1 more source

Isolated primary amyloidosis of the inferior rectus muscle mimicking Graves’ orbitopathy

open access: yesEinstein (São Paulo)
The diagnosis of Graves’ orbitopathy is usually straightforward. However, orbital diseases that mimick some clinical signs of Graves’ orbitopathy may cause diagnostic confusion, particularly when associated to some form of thyroid dysfunction.
Mário Luiz Ribeiro Monteiro   +2 more
doaj   +1 more source

Factors affecting the course of Graves' Orbitopathy and poor response to glucocorticoid treatment followed by orbital radiotherapy [PDF]

open access: yes, 2022
Graves’ orbitopathy is a rare autoimmune disorder characterized by the inflammation of orbital tissues. The course of disease can be described in terms of its activity and severity.
Sokołowski, Andrzej   +9 more
core   +2 more sources

Current Knowledge on Graves’ Orbitopathy [PDF]

open access: yesJournal of Clinical Medicine, 2020
(1) Background: Graves’ orbitopathy (GO) is an autoimmune inflammation of the orbital tissues and the most common extra-thyroid symptom of Graves’ disease (GD). Mild cases of GO are often misdiagnosed, which prolongs the diagnostic and therapeutic process, leading to exacerbation of the disease. A severe course of GO may cause permanent vision loss. (2)
Katarzyna Gontarz-Nowak   +4 more
openaire   +2 more sources

Graves' orbitopathy treated with immunosuppressive therapy and orbital radiotherapy in a tertiary care endocrine centre: case series

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2016
Graves’ Orbitopathy (GO) is a localized entity of Graves’ disease, which is a challenging disease to treat. We describe 6 cases of moderate to severe GO who presented to our endocrine centre, with a mean age of 48.6 years and equal gender distribution ...
D. C. Kottahachchi   +4 more
doaj   +1 more source

Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]

open access: yesHormone and Metabolic Research, 2015
AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P   +3 more
openaire   +3 more sources

Successful outcome of Rituximab treatment based on lymphocyte immunophenotyping in active Thyroid Eye Disease: a case report

open access: yesThyroid Research
Background Rituximab, an anti-CD20 monoclonal antibody that depletes B-cells, is a potential second-line treatment for moderate-to-severe active Thyroid Eye Disease that is resistant to steroids.
Mirco Armenti   +6 more
doaj   +1 more source

Genetic profiling of orbital fibroblasts from patients with Graves' orbitopathy

open access: yes, 2021
Graves' orbitopathy (GO) is an autoimmune disease persisting when immunosuppression is achieved. Orbital fibroblasts from GO patients display peculiar phenotypes even if not exposed to autoimmunity, possibly reflecting genetic or epigenetic mechanisms ...
Dottore, Giovanna Rotondo   +36 more
core   +1 more source

The Value of Multidetector Computed Tomography of Orbits in Globe Protrusion in Comparison to Hertel Exophthalmometry

open access: yesActa Clinica Croatica, 2017
The use of multidetector computed tomography (MDCT) is an integral part of contemporary diagnostics of Graves‘ orbitopathy. Th e aim of this study was to assess proptosis measurement by MDCT and to compare it to the current standard, Hertel ...
Igor Đorić   +7 more
doaj   +1 more source

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