Results 41 to 50 of about 4,410 (137)

The change in the clinical presentation of Graves’ disease: a 30 years retrospective survey in an academic Brazilian tertiary center

open access: yesArchives of Endocrinology and Metabolism, 2020
Objective Graves’ disease (GD) is the main cause of hyperthyroidism among adults. It is an autoimmune condition classically marked by the Merserburg Triad (goiter, thyrotoxicosis, and orbitopathy), but the change in presentation of GD over time has ...
Wanesa Pinto   +4 more
doaj   +1 more source

Medical Treatment of Graves’ Orbitopathy

open access: yesHormone and Metabolic Research, 2015
The medical treatment of Graves' orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20-30% of patients are not responsive and about 20% present with disease recurrence.
Salvi, M., Campi, I.
openaire   +2 more sources

Isolated primary amyloidosis of the inferior rectus muscle mimicking Graves’ orbitopathy

open access: yesEinstein (São Paulo)
The diagnosis of Graves’ orbitopathy is usually straightforward. However, orbital diseases that mimick some clinical signs of Graves’ orbitopathy may cause diagnostic confusion, particularly when associated to some form of thyroid dysfunction.
Mário Luiz Ribeiro Monteiro   +2 more
doaj   +1 more source

Graves' orbitopathy treated with immunosuppressive therapy and orbital radiotherapy in a tertiary care endocrine centre: case series

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2016
Graves’ Orbitopathy (GO) is a localized entity of Graves’ disease, which is a challenging disease to treat. We describe 6 cases of moderate to severe GO who presented to our endocrine centre, with a mean age of 48.6 years and equal gender distribution ...
D. C. Kottahachchi   +4 more
doaj   +1 more source

Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]

open access: yesHormone and Metabolic Research, 2015
AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P   +3 more
openaire   +3 more sources

Endoscopic orbital decompression for Graves′ orbitopathy

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Aim: To study the efficacy of endonasal endoscopic orbital decompression in cases of Graves′ orbitopathy. Material and Methods: A total of 24 orbits in 12 patients underwent endoscopic orbital decompression for graves orbitopathy in the period between ...
Priti Lal, Alok Thakar, Nikhil Tandon
doaj   +1 more source

Successful outcome of Rituximab treatment based on lymphocyte immunophenotyping in active Thyroid Eye Disease: a case report

open access: yesThyroid Research
Background Rituximab, an anti-CD20 monoclonal antibody that depletes B-cells, is a potential second-line treatment for moderate-to-severe active Thyroid Eye Disease that is resistant to steroids.
Mirco Armenti   +6 more
doaj   +1 more source

The Value of Multidetector Computed Tomography of Orbits in Globe Protrusion in Comparison to Hertel Exophthalmometry

open access: yesActa Clinica Croatica, 2017
The use of multidetector computed tomography (MDCT) is an integral part of contemporary diagnostics of Graves‘ orbitopathy. Th e aim of this study was to assess proptosis measurement by MDCT and to compare it to the current standard, Hertel ...
Igor Đorić   +7 more
doaj   +1 more source

Significance of HLA in Graves’ disease and Graves’ orbitopathy in Asian and Caucasian populations – a systematic review

open access: yesFrontiers in Immunology, 2023
IntroductionGraves’ disease (GD) and Graves’ orbitopathy (GO) development were suspected to be HLA-related in both Asian and Caucasian populations. However, most studies were performed with application of serological methods or low resolution genetic ...
Magdalena Stasiak   +4 more
doaj   +1 more source

Effectiveness of Selenium Supplementation in the Treatment of Graves–Basedow Disease: A Scoping Review

open access: yesMedical Sciences
Background: Graves–Basedow disease (GBD) is an autoimmune thyroid disorder characterized by loss of tolerance to the thyrotropin receptor, with clinical manifestations such as a hyperadrenergic state, goiter, orbitopathy, and myxedema, inter alia ...
Hernando Vargas-Uricoechea   +5 more
doaj   +1 more source

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