Results 51 to 60 of about 224,706 (187)
Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]
Hormone and Metabolic Research, 2015 AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P +3 more
openaire +3 more sources
Thyroid ResearchBackground Rituximab, an anti-CD20 monoclonal antibody that depletes B-cells, is a potential second-line treatment for moderate-to-severe active Thyroid Eye Disease that is resistant to steroids.
Mirco Armenti +6 more
doaj +1 more source
JGH Open, Volume 10, Issue 7, July 2026.ABSTRACT Aims Despite the recommendation of steroid therapy for type 1 autoimmune pancreatitis (AIP), the value of steroid pulse therapy remains unclear. This study aimed to assess the efficacy and safety of steroid pulse therapy in patients with AIP. Methods and Results Of 121 patients with type 1 AIP who were identified, 116 with adequate follow‐up ...
Akihisa Adachi +11 more
wiley +1 more source
Acta Clinica Croatica, 2017 The use of multidetector computed tomography (MDCT) is an integral part of contemporary diagnostics of Graves‘ orbitopathy. Th e aim of this study was to assess proptosis measurement by MDCT and to compare it to the current standard, Hertel ...
Igor Đorić +7 more
doaj +1 more source
Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease
Advanced Science, Volume 13, Issue 27, 13 May 2026.This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang +15 more
wiley +1 more source
Frontiers in Immunology, 2023 IntroductionGraves’ disease (GD) and Graves’ orbitopathy (GO) development were suspected to be HLA-related in both Asian and Caucasian populations. However, most studies were performed with application of serological methods or low resolution genetic ...
Magdalena Stasiak +4 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 4, April 2026.ABSTRACT Background and Aims Coronavirus disease‐2019 (COVID‐19) emerged in 2019 from Wuhan, China, leading to the accelerated development of vaccines, which have proven instrumental in controlling the spread of the virus. While vaccination ceased the increasing trend of the viral infection, rare adverse autoimmune events emerged as important ...
Mohammad Javad Yousefi‐Hashemabad +6 more
wiley +1 more source
Factors affecting the course of Graves' Orbitopathy and poor response to glucocorticoid treatment followed by orbital radiotherapy [PDF]
, 2022 Graves’ orbitopathy is a rare autoimmune disorder characterized by the inflammation of orbital tissues. The course of disease can be described in terms of its activity and severity.
Sokołowski, Andrzej +4 more
core +2 more sources
Medical SciencesBackground: Graves–Basedow disease (GBD) is an autoimmune thyroid disorder characterized by loss of tolerance to the thyrotropin receptor, with clinical manifestations such as a hyperadrenergic state, goiter, orbitopathy, and myxedema, inter alia ...
Hernando Vargas-Uricoechea +5 more
doaj +1 more source
The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.Abstract Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic ...
Alex Jenei +10 more
wiley +1 more source