Results 241 to 250 of about 364,671 (298)

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

open access: yesAdvanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li   +8 more
wiley   +1 more source

Initial Treatment of Pediatric Graves' Disease with Methimazole: A Retrospective Follow-up Study

open access: bronze, 2010
Rie Matsushita   +11 more
openalex   +2 more sources

Ultra‐Sensitive and Linear Flexible Pressure Sensors with Tri‐Scale Graded Microstructures for Advanced Health Monitoring and Robotic Perception

open access: yesAdvanced Science, EarlyView.
A flexible piezoresistive sensor with a 3D tri‐scale graded microstructure is proposed, overcoming the trade‐off between sensitivity and linearity. The device achieves ultra‐high sensitivity (138.6 kPa−1), a broad linear range (400 kPa, R2 = 0.99), and exceptional stability (24 000 repeated loading cycles), enabling precise detection of physiological ...
Rui Chen   +6 more
wiley   +1 more source

Graves' ophthalmopathy

open access: yesSwiss Medical Weekly, 2002
Swiss Medical Weekly
doaj   +1 more source

Accumulation of Identical T Cell Clones in the Right and Left Lobes of the Thyroid Gland in Patients with Graves' Disease. Analysis of T Cell Clonotype in vivo.

open access: bronze, 2000
Taichi Sekine   +7 more
openalex   +2 more sources

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

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