Steroid Treatment Focused Management of Graves’ Ophthalmopathy
Graves' disease (GD) is an autoimmune disease that affects the thyroid and the eyes. Graves' ophthalmopathy (GO), an autoimmune disease, usually appears 18 months after GD diagnosis.
Condeng Y. H.+5 more
doaj +1 more source
A Literature Review of Concomitant Primary Biliary Cirrhosis and GravesÂ’ Disease
Although Hashimoto’s thyroiditis (HT) is commonly characterized by extrahepatic manifestations of primary biliary cirrhosis (PBC), coexistence of PBC and Graves’ disease (GD) is uncommon. This is a review of the English and Japanese scientific literature, comprising 7 cases of PBC and GD coexistence. All patients were female.
openaire +2 more sources
Figure S1. MR imaging of cerebral infarction in the first episode. Axial diffusion-weighted images showed infarcts in the left cerebral hemisphere. (PDF 202 kb)
Ito, Hiroto+9 more
openaire +1 more source
Unilateral Graves’ Orbitopathy in a patient with Marine-Lenhart Syndrome: A case report [PDF]
Thyroid eye disease (TED) is the most common symptoms of Graves’ disease. This condition commonly manifests bilaterally and symmetrically. The most prominent symptoms are lid retraction, exophthalmos, and diplopia.
Al Farqani, Ahmed+6 more
core +2 more sources
An uncommon case of Marine-Lenhart syndrome [PDF]
The term Marine-Lenhart syndrome describes the association between Graves' disease and autonomously functioning thyroid nodules (AFTN), such as toxic adenoma or toxic multinodular goiter.
Alfredo Campennì+6 more
core +2 more sources
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Mixture of Input-Output Hidden Markov Models for Heterogeneous Disease Progression Modeling [PDF]
A particular challenge for disease progression modeling is the heterogeneity of a disease and its manifestations in the patients. Existing approaches often assume the presence of a single disease progression characteristics which is unlikely for neurodegenerative disorders such as Parkinson's disease.
arxiv
Neonatal hyperthyroidism: clinical pattern and therapy [PDF]
Neonatal hyperthyroidism is a rare pathology, most often the consequence of Graves' disease in the mother. Around 0.2% of pregnant women have Graves disease and 1 to 2% of newborns of mother with Graves' disease.
LEBRETHON, Marie-Christine+4 more
core
Occurrence of Type 1 Diabetes in Graves' Disease Patients Who Are Positive for Antiglutamic Acid Decarboxylase Antibodies: An 8-Year Followup Study [PDF]
Glutamic acid decarboxylase antibodies (GADAs) are one of the markers of islet cell autoimmunity and are sometimes present before the onset of type 1 diabetes (T1D).
Ito, Koichi+3 more
core +3 more sources