Results 61 to 70 of about 7,511 (159)
Thyroid associated orbitopathy
Thyroid associated orbitopathy, also known as Graves′ orbitopathy, is typically a self-limiting autoimmune process associated with dysthyroid states.
Rajat Maheshwari, Ezekiel Weis
doaj +1 more source
Imaging of adult ocular and orbital pathology - a pictorial review [PDF]
Orbital pathology often presents a diagnostic challenge to the reporting radiologist. The aetiology is protean, and clinical input is therefore often necessary to narrow the differential diagnosis.
Brennan, Paul +8 more
core +1 more source
ABSTRACT Photoreceptor transplantation is being studied to restore visual function in retinal diseases causing blindness, including age‐related macular degeneration, hereditary eye diseases, and traumatic retinopathy. Preclinical studies often involve delivering exogenous human photoreceptor cells into animal models' retinas.
Kang V. Li +14 more
wiley +1 more source
Association between G protein polymorphisms (GNAS1 T393C and GNB3 C825T) and course of Graves’ disease and Graves’ orbitopathy [PDF]
Summary The biology of initiation and progression of Graves’ hyperthyroidism and Graves’ orbitopathy is complex. For the individually tailored therapy of the diseases it is very important to identify the risk factors.
Dmuchowska, Diana
core
Extra-ocular muscle MRI in genetically-defined mitochondrial disease [PDF]
Conventional and quantitative MRI was performed in patients with chronic progressive external ophthalmoplegia (CPEO), a common manifestation of mitochondrial disease, to characterise MRI findings in the extra-ocular muscles (EOMs) and investigate whether
Cathy Woodward +12 more
core +1 more source
Glymphatic System Dysfunction in Thyroid‐Associated Ophthalmopathy: A Multimodal MRI Study
TAO patients exhibit impaired glymphatic function, with reduced DTI‐ALPS indices and gBOLD‐CSF coupling, but unchanged choroid plexus volume. These alterations correlate with neuropsychological symptoms and sleep disturbances. Restoring glymphatic activity may offer a therapeutic approach to enhance patient outcomes.
Lijie Zhang +4 more
wiley +1 more source
Alemtuzumab-induced thyroid eye disease successfully treated with a single low dose of rituximab
Introduction: Secondary thyroid autoimmunity, especially Graves’ disease (GD), frequently develops in patients with multiple sclerosis (MS) following alemtuzumab treatment (ALTZ; anti-CD52). Thyroid eye disease (TED) can also develop, and rituximab (RTX;
Ilaria Muller +10 more
doaj +1 more source
Clinical assessment of patients with Graves' orbitopathy [PDF]
Clinical examination is the basis of a good assessment of a patient with Graves' orbitopathy. This study gives recommendations of the European orbitopathy group related to the activity and severity of the disease. The activity of the disease is estimated
Nedeljković-Beleslin Biljana
doaj +1 more source
Orbital pseudotumour masquerading as Wegener’s granulomatosis [PDF]
A twenty-two year old female patient presented with new onset bilateral hard orbital masses and progressively worse tear lake problems. Computed tomography of the orbits revealed poorly differentiated bilateral orbital masses.
Fenech, Matthew, Fenech, Thomas
core
Endoscopic orbital decompression for Graves' ophthalmopathy [PDF]
Graves’ disease may occasionally result in significant proptosis that is either cosmetically unacceptable or causes visual loss. This has traditionally been managed surgically by external decompression of the orbital bony skeleton. Trans-nasal endoscopic
Carney, A. +3 more
core +1 more source

