Results 31 to 40 of about 9,066 (175)

Oftalmopatía tiroidea: determinación de parámetros de actividad clínica de la oftalmopatía tiroidea como factor pronóstico de respuesta al tratamiento inmunosupresor [PDF]

, 2005
Objective: To determine the usefulness of the clinical, biochemical and thyroid imaging parameters in patients with thyroid-associated ophthalmopathy, in predicting their response to immunosuppressive treatment.
Belzunce, A. (Arnaldo), Casellas, M. (M.), Garcia-Gomez, P.J. (Pío J.), Heras-Mulero, H. (Henar), Moreno-Montañes, J. (Javier)   +4 more
core   +1 more source

Graves’ ophthalmopathy – thyroid eye disease

Journal of Education, Health and Sport, 2019
Graves’ disease (GD) is an autoimmune disorder that affects thyroid. It is caused by antibody, named thyroid-stimulating immunoglobulin (TIS) that acts like thyroid stimulating hormone (TSH), resulting in thyroid hormone overproduction – condition called
Dagna Siedlecka, Wojciech Micał, Ewa Krzewicka-Romaniuk, Rashed Mustafa Nazzal   +3 more
doaj   +3 more sources

Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts–a possible explanation of the link between smoking and Graves’ ophthalmopathy

International Journal of Ophthalmology, 2014
AIM: To assess the effects of hypoxia on human orbital fibroblasts (OF) on adipogenesis and adipocytokine production.METHODS:Human OF were derived from tissues obtained from patients with Graves’ ophthalmopathy (GO) and from patients without known ...
Chiaw Ling Chng, Oi Fah Lai, Charmaine Sze-Min Chew, Yu Pei Peh, Stephanie Man-Chung Fook-Chong, Lay Leng Seah, Daphne Hsu-Chin Khoo   +6 more
doaj   +1 more source

Extraocular muscle repositioning as the last therapeutic option for a patient with a severe course of Graves’ Ophthalmopathy: a case report

BMC Ophthalmology, 2018
Background Graves’ disease is a common autoimmune inflammatory condition of the thyroid. About one in four of affected patients also develop orbital symptoms like exophthalmos, proptosis and diplopia - called Graves’ Ophthalmopathy.
Andrea Rau, Matthias Klopfer, Niklas Rommel, Mechthild Rau-Fornefeld, Andreas Kolk   +4 more
doaj   +1 more source

Novel observational study protocol to develop a prediction model that identifies patients with Graves’ ophthalmopathy insensitive to intravenous glucocorticoids pulse therapy

BMJ Open, 2021
Introduction Intravenous glucocorticoids pulse therapy is the first-line treatment for moderate-to-severe and active Graves’ ophthalmopathy, with a large proportion of patients having poor efficacy and exposed to the risk of glucocorticoids adverse ...
Jing Sun, Lunhao Li, Yinwei Li, Xuefei Song, Huifang Zhou   +4 more
doaj   +1 more source

World thyroidology news

Клиническая и экспериментальная тиреоидология, 2014
The article is to overview papers: Effect of vitamin C on the absorption of levothyroxine in patients with hypothyroidism and gastritis. Management of neonates born to women with Graves’ disease: a cohort study.
Yuliya Aleksandrovna Manuylova, Anna Evgenyevna Shvedova   +1 more
doaj   +1 more source

Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells [PDF]

, 2015
Introduction Patients with autoimmune thyroid disease (AITD) show defects in their immune-regulatory mechanisms. Herein we assessed the expression and function of galectin-1 and galectin-9 (Gal-1, Gal-9) in dendritic cells (DCs) from patients with ...
Ana Ramos-Levi, Ana Rodríguez-Muñoz, Ana Serrano, AP Weetman, BS Prabhakar, C Blaser, C Mao, D Cooper, FC Chou, Francisco Sánchez-Madrid, GA Rabinovich, H de la Fuente, Hortensia de la Fuente, ID Mascanfroni, J van der Leij, L Bartalena, L Monney, LV Norling, M Demetriou, M Kanzaki, M Marazuela, M Ruiz-Riol, M Seki, M Seki, MA Toscano, Miguel Sampedro-Nuñez, Mónica Marazuela, N Figueroa-Vega, N Figueroa-Vega, NL Perillo, Roberto González-Amaro, S Katoh, S Leskela, Silke Appel, Susanna Leskela, T Arikawa, T Imaizumi, WM Wiersinga   +37 more
core   +5 more sources

Modified Deep Lateral Wall Decompression Surgery in the Treatment of Thyroid‐Associated Ophthalmopathy: A Retrospective Evaluation

Eye &ENT Research, Volume 3, Issue 1, Page 5-10, March 2026.
ABSTRACT Background Thyroid‐associated ophthalmopathy (TAO) may lead to severe exophthalmos and dysthyroid optic neuropathy (DON), which can threaten visual function. Orbital decompression surgery is often required when medical therapy is insufficient; however, traditional deep lateral wall decompression techniques remain associated with several ...
Shuo Wu, Jiahong Lao, Rongrong Ge, Zhaohui Shi, Qintai Yang   +4 more
wiley   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

MedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu, Congcong Yan, Lu Chen, Weijie Liu, Xiaozhou Hu, Mengyuan Gao, Wei Rao, Jiayi Zhang, Junye Zhu, Hui Wu, Kang Zhang, Meng Zhou, Wencan Wu   +12 more
wiley   +1 more source

The Diagnostic Value of Mean Apparent Propagator‐MRI in Dysthyroid Optic Neuropathy: A Quantitative Analysis of the Entire Visual Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The diagnostic model combining orbital and intracranial MAP‐MRI parameters could significantly optimize diagnostic efficiency of dysthyroid optic neuropathy. Comprehensive MAP‐MRI parameters analysis of the entire visual pathway enables a deeper understanding of disease involvement, provides novel insights into the early accurate diagnosis and ...
Mengsha Zou, Dide Wu, Yanglei Cheng, Haodong Qin, Zhiyun Yang, Shubin Hong, Hongzhang Zhu, Cui Yan   +7 more
wiley   +1 more source