Results 31 to 40 of about 1,530,432 (282)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Sari PediatriLatar belakang. Penyakit Graves (PG) merupakan kelainan autoimun yang merupakan penyebab hipertiroid terbanyak pada anak dan remaja. Manifestasi PG dan proses pengobatan yang dilakukan pasien akan memberikan dampak pada kualitas hidup pasien.
Ismi Citra Ismail +6 more
doaj +1 more source
Pallas, 2014 During the Early Iron Age in Macedonia, metallic finds seem to occupy a more prominent place in graves than the ceramic vessels. In the necropolis of Vergina, the weapons for men and jewelries for women obviously work together to specify the social ...
Anne-Zahra Chemsseddoha
doaj +1 more source
Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters
Frontiers in Endocrinology, 2022 There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect
Lilly H. Wagner +5 more
doaj +1 more source
Effects of age, density, and seasonality on molt pattern in the mammal genus (Peromyscus) [PDF]
, 2015 Molting, or replacement of pelage (hair) in mammals, occurs during ontogeny as individuals transition from juveniles to adults. Environmental factors can cause variation in molt in many species for thermoregulatory and camouflage purposes.
Graves, Rebecca Catherine
core +1 more source
Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]
Hormone and Metabolic Research, 2015 AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P +3 more
openaire +3 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source