Results 41 to 50 of about 229,925 (308)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Thyroid sonography as an extension of the bedside examination in hyperthyroidism
Journal of Medical Science, 2020 In this mini-review, we discuss the role of thyroid sonography as a ‘point-of-care’ tool for assessing and managing patients with (suspected) hyperthyroidism who present to the endocrine outpatient clinic.
Angelos Kyriacou +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Notes on the metal pyxides recently discovered in the Sarmatian environment south the Lower Mureș River [PDF]
Plural: History, Culture, Society, 2017 This study, although not exhaustive, attempts to analyse pieces of the type discovered in the Sarmatian environment of the Great Hungarian Plain starting from the bronze and iron pyxides discovered in 2010 during the rescue archaeological excavations ...
Vitalie Bârcă
doaj
Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters
Frontiers in Endocrinology, 2022 There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect
Lilly H. Wagner +5 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Letter: Walter H. Graves to Ida M. Tarbell, February 1907
, 1902 Handwritten letter, 2 pages.
Graves, Walter H.
core +1 more source
Materiale și Cercetări Arheologice, 2018 The aim of this study is to provide extensive information regarding the results of the archaeological research carried out during the autumn of 2017 in Coada Izvorului locality, Măneşti commune (Prahova County).
Frînculeasa, A. +3 more
doaj +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source