Results 41 to 50 of about 311,650 (281)
Notes on the origin and dating of the bone pyxides from the Sarmatian environment between the Don and the Prut [PDF]
Plural: History, Culture, Society, 2019 The object of this article is to discuss the bone pyxides discovered in the Sar¬matian graves from the north and north-west of the Black Sea. The study, with¬out being exhaustive, attempts a presentation of the graves where bone pyxides were identified ...
Vitalie Bârcă
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Diagnostic and Follow-up Characteristics of Cases Presenting with Hyperthyroidism in Childhood
Güncel PediatriIntroduction: Hyperthyroidism is a disease characterized by high total T4, T3, free T4, T3, and suppressed thyroid stimulating hormone (TSH), most seen in childhood due to Graves’ disease. This study aimed to examine the diagnostic features and treatment
Yasemin Denkboy Öngen, Özlem Kara
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Thyroid sonography as an extension of the bedside examination in hyperthyroidism
Journal of Medical Science, 2020 In this mini-review, we discuss the role of thyroid sonography as a ‘point-of-care’ tool for assessing and managing patients with (suspected) hyperthyroidism who present to the endocrine outpatient clinic.
Angelos Kyriacou +2 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Notes on the metal pyxides recently discovered in the Sarmatian environment south the Lower Mureș River [PDF]
Plural: History, Culture, Society, 2017 This study, although not exhaustive, attempts to analyse pieces of the type discovered in the Sarmatian environment of the Great Hungarian Plain starting from the bronze and iron pyxides discovered in 2010 during the rescue archaeological excavations ...
Vitalie Bârcă
doaj