Results 41 to 50 of about 301,894 (280)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Thyroid sonography as an extension of the bedside examination in hyperthyroidism
Journal of Medical Science, 2020 In this mini-review, we discuss the role of thyroid sonography as a ‘point-of-care’ tool for assessing and managing patients with (suspected) hyperthyroidism who present to the endocrine outpatient clinic.
Angelos Kyriacou +2 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Notes on the metal pyxides recently discovered in the Sarmatian environment south the Lower Mureș River [PDF]
Plural: History, Culture, Society, 2017 This study, although not exhaustive, attempts to analyse pieces of the type discovered in the Sarmatian environment of the Great Hungarian Plain starting from the bronze and iron pyxides discovered in 2010 during the rescue archaeological excavations ...
Vitalie Bârcă
doaj
Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters
Frontiers in Endocrinology, 2022 There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect
Lilly H. Wagner +5 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Enclosure – Letter from David Graves
, 1938 Page from Robert Graves diary manuscript. The diary includes 1,546 pages with 117 enclosures: letters, clippings, photographs post cards, notes ...
Graves, Robert, 1895-1985
core +1 more source
Materiale și Cercetări Arheologice, 2018 The aim of this study is to provide extensive information regarding the results of the archaeological research carried out during the autumn of 2017 in Coada Izvorului locality, Măneşti commune (Prahova County).
Frînculeasa, A. +3 more
doaj +1 more source