Results 31 to 40 of about 1,543,350 (297)
Echo State Networks: analysis, training and predictive control
, 2019 The goal of this paper is to investigate the theoretical properties, the training algorithm, and the predictive control applications of Echo State Networks (ESNs), a particular kind of Recurrent Neural Networks. First, a condition guaranteeing incremetal
albertini +12 more
core +1 more source
Intraorbital Steroid Injection for Active Thyroid Ophthalmopathy
Journal of Ophthalmic & Vision Research, 2020 Purpose: To evaluate the effect of orbital steroid injections in patients with active thyroid ophthalmopathy resistant to or dependent on systemic steroids, or with complications related to systemic steroid use.
Abbas Bagheri +2 more
doaj +1 more source
Sophía: Colección de Filosofía de la Educación, 2013 El presente trabajo constituye una alegoría didáctica en donde los filósofos Galileo Galilei (1564-1642) y Aristóteles (384 a.C–322 a.C), en una simulada confrontación de criterios, debaten ante un tribunal científico moderno para dilucidar quién tuvo ...
Franklin Erazo
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
What has changed in thyroid eye disease in the last five years (2020–2025)
European Thyroid JournalBackground: Significant progress has been made in the management of thyroid eye disease (TED), based on the elucidation of important pathogenic mechanisms. This has led to novel therapeutics validated in randomized clinical trials.
Mario Salvi
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence Transduction with Recurrent Neural Networks [PDF]
, 2012 Many machine learning tasks can be expressed as the transformation---or \emph{transduction}---of input sequences into output sequences: speech recognition, machine translation, protein secondary structure prediction and text-to-speech to name but a few ...
Graves, Alex
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Modeling Graves’ Orbitopathy in Experimental Graves’ Disease [PDF]
Hormone and Metabolic Research, 2015 AbstractGraves’ orbitopathy (GO), also known as thyroid eye disease is an inflammatory disease of the orbital tissue of the eye that arises as a consequence of autoimmune thyroid disease. The central feature of the disease is the production of antibodies to the thyrotropin hormone receptor (TSHR) that modulate the function of the receptor leading to ...
Banga, J P +3 more
openaire +3 more sources