Results 71 to 80 of about 10,411,269 (304)

Moral reasoning and gray matter volume.

open access: yes, 2015
Increased gray matter volume was found in the bilateral vmPFC/sgACC for participants who reached the post-conventional level (n = 38) of moral development compared to participants who did not reach that level (n = 29).
Hengyi Rao (418099)   +5 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

White matter lesions and brain gray matter volume in cognitively normal elders [PDF]

open access: yesNeurobiology of Aging, 2012
Cerebral white matter lesions (WMLs) reflect small vessel disease, are common in elderly individuals, and are associated with cognitive impairment. We sought to determine the relationships between WMLs, age, gray matter (GM) volume, and cognition in the Cardiovascular Health Study (CHS).
Cyrus A, Raji   +9 more
openaire   +2 more sources

Other title: Inset title: Entrance to Mobile Bay

open access: yes, 1884
Copyright, 1878, by O.W. Gray & Son; Bottom margin center: Philadelphia : O.W. Gray & Son; Right margin: 82, 83; Prime meridians: Washington and Greenwich.; Marked off in ranges and townships.; Relief shown by hachures and soundings.; Inset: Entrance to ...
Gray, Frank A.
core   +1 more source

Cortical Damage Associated With Cognitive and Motor Impairment in Hereditary Spastic Paraplegia: Evidence of a Novel SPAST Mutation

open access: yesFrontiers in Neurology, 2020
To determine the cortical mechanism that underlies the cognitive impairment and motor disability in hereditary spastic paraplegia (HSP), nine HSP patients from a Chinese family were examined using clinical evaluation, cognitive screening, and genetic ...
Jian-zhong Lin   +8 more
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Cortical gray matter volume deficits in schizophrenia: a replication

open access: yesSchizophrenia Research, 1996
We sought to replicate an earlier finding of widespread deficit in cortical gray matter in schizophrenia by testing new samples of 22 schizophrenic patients and 27 controls between the ages of 21-46 years. Brain values for both patients and controls were standardized against age and head size norms derived from a larger control group (n = 73) spanning ...
K O, Lim   +3 more
openaire   +2 more sources

Brain regions showing group differences in gray matter volume.

open access: yes, 2023
Brain regions showing group differences in gray matter volume.
Rui Liu (54031)   +4 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Brain structural and neurofunctional correlates of liability to psychosis : a multimodal neuroimaging approach [PDF]

open access: yes, 2011
Schizophrenia is one of the most debilitating and still not entirely understood mental diseases. Improvements in the treatment came hand in hand with an introduction of antipsychotics and thus with better understanding of neurobiology underlying its ...
Smieskova, Renata
core   +1 more source

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