Results 111 to 120 of about 135,918 (287)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Review of source models for reproducing and predicting strong motions by empirical Green's function method

open access: yesJapan Architectural Review
Short‐period ground motions from earthquakes are calculated by semiempirical methods such as the empirical Green's function method or the stochastic Green's function method.
Kazuo Dan
doaj   +1 more source

REDUCED p-MODULUS, p-HARMONIC RADIUS AND p-HARMONIC GREEN’S MAPPINGS

open access: yesПроблемы анализа, 2018
We consider the definitions and properties of the metric characteristics of the spatial domains previously introduced by the author, and their connection with the class of mappings, the particular case of which are the harmonic Green’s mappings ...
B. E. Levitskii
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

THE ALL-SOURCE GREEN’S FUNCTION AND ITS APPLICATIONS TO TSUNAMI PROBLEMS [PDF]

open access: yesScience of Tsunami Hazards, 2007
The classical Green’s function provides the global linear response to impulse forcing at a particular source location. It is a type of one-source-all-receiver Green’s function.
ZHIGANG XU
doaj  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy