Results 91 to 100 of about 960,262 (264)

Simulating crowding of urban green areas to manage access during lockdowns. [PDF]

Landsc Urban Plan, 2022
Geneletti D, Cortinovis C, Zardo L.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Chloroplast phylogenomics provides new evidence for reevaluating the taxonomic placement of medicinal Agapetes

Frontiers in Plant Science
Species of Agapetes are recognized for their radish-like tubers, which possess significant medicinal properties. Resolving the long-standing phylogenetic controversies between Agapetes and its relatives is crucial for facilitating the utilization of this
Jindong Wang, Jindong Wang, Jindong Wang, Baizhu Li, Yunjing Liu, Yunjing Liu, Yunjing Liu, Yu Li, Yin Yi, Yin Yi, Yin Yi, Wei Xie, Wei Xie, Wei Xie, Xiaoxin Tang, Xiaoxin Tang, Xiaoxin Tang, Xiaoxin Tang   +17 more
doaj   +1 more source

Establishment and Expansion of Harmonia axyridis Pallas (Coleoptera: Coccinellidae) in Urban Green Areas in the Iberian Peninsula: From 2015 to 2021. [PDF]

Insects, 2022
Meseguer R, Lumbierres B, Pons X.
europepmc   +1 more source

PLANNING OF GREEN AREAS IN CITY AREAS

The rapid development of the city in vertical and horizontal directions sharply reduces the attractiveness of the landscape of the area. Interesting natural objects - parks, beautiful hills, banks of rivers and lakes, terraces on the plain, if they are preserved and organically included in the system of urban green spaces, in forming the environment of
openaire   +2 more sources

Environmental Green Area Recovery

, 2013
Green areas have been historically managed in an inappropriate manner towards their purposes of urban as well as environmental character, undermining the biota. These areas are typically governed by development plans which are proposed by the municipality. However, proposals are also taken by the community to competent bodies. Then, it was tried to fit
Pandolfo, Adalberto, A., Neckel, A., Bisognin, E., Goellner, L.M., Pandolfo, L.D., Tagliari   +5 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

COVID-19 epidemic spread and green areas Italy and Spain between 2020 and 2021: An observational multi-country retrospective study. [PDF]

Environ Res, 2023
Falco A, Piscitelli P, Vito D, Pacella F, Franco C, Pulimeno M, Ambrosino P, Arias J, Miani A.   +8 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source