Results 71 to 80 of about 960,262 (264)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Bat-parasite interaction networks in urban green areas in northeastern Brazil. [PDF]
Parasitology, 2023 Bezerra RHS, Bocchiglieri A.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Principles and proposals for norm formation of Lithuanian green areas
Journal of Architecture and Urbanism, 2007 In this paper norms of urban green areas formed by the order of the Ministry of Environment are presented. The current legislation of Lithuanian green areas as a component of urban structure is surveyed.
Konstantinas Jakovlevas-Mateckis +2 more
doaj +1 more source
The potential of swimming pool rinsing water for irrigation of green areas: a case study. [PDF]
Environ Sci Pollut Res Int, 2023 Poćwiardowski W.
europepmc +1 more source
, 2019 This paper studies the size and location of urban green areas across city spaces. Urban green areas offer amenities that affect residential choices, land consumption and land rent. This paper discusses the socially optimal sizes and locations of urban green areas within a city and their decentralized allocation through land markets.
PICARD, Pierre M, TRAN, Thi Thu Huyen
openaire +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
How do urbanization and alien species affect the plant taxonomic, functional, and phylogenetic diversity in different types of urban green areas? [PDF]
Environ Sci Pollut Res Int, 2023 Dylewski Ł +3 more
europepmc +1 more source