Results 91 to 100 of about 11,608,149 (298)

Metal–carbene-guided twofold cross-coupling of ethers with chromium catalysis

Nature Communications
Coupling by metal–carbene transfer enables the formation of several different bonds at the carbenoid site, enabling prochiral Csp 3 centers that are fundamental three-dimensional substructures for medicines to be forged with increased efficiency. However,
Fei Fan, Yong Peng, Xiaoyu Zhang, Sha Wang, Zheng Luo, Meiming Luo, Xiaoming Zeng   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The implementation of practical work in chemistry, along with the principles of green chemistry and sustainable chemistry, in Portugal

Chemistry Teacher International
Since the late twentieth century, global sustainability and greener chemistry have become essential human goals. Education is crucial in driving this change by enhancing scientific knowledge and literacy.
Ribau Isabel
doaj   +1 more source

Chromium-catalyzed para-selective formation of quaternary carbon centers by alkylation of benzamide derivatives

Nature Communications, 2018
The selective installation of quaternary carbon substituents on arenes is a highly challenging synthetic goal. Here, the authors report a chromium-catalyzed para-selective functionalization of benzamides with tertiary organometallic reagents under mild ...
Pei Liu, Changpeng Chen, Xuefeng Cong, Jinghua Tang, Xiaoming Zeng   +4 more
doaj   +1 more source

CALB Immobilized onto Magnetic Nanoparticles for Efficient Kinetic Resolution of Racemic Secondary Alcohols: Long-Term Stability and Reusability

Molecules, 2019
In this study, an immobilization strategy for magnetic cross-linking enzyme aggregates of lipase B from Candida antarctica (CALB) was developed and investigated. Magnetic particles were prepared by conventional co-precipitation.
Xiu Xing, Jun-Qi Jia, Jing-Fan Zhang, Zi-Wen Zhou, Jun Li, Na Wang, Xiao-Qi Yu   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Towards Eco-Reflexive Science Education : A Critical Reflection About Educational Implications of Green Chemistry

, 2016
The modern world can be described as a globalised risk society. It is characterized by increasing complexity, unpredictable consequences of techno-scientific innovations and production, and its environmental consequences.
Zuin, Vania,, Sjöström, Jesper,, Eilks, Ingo,   +2 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Synthesis and redox catalysis of Carbodiphosphorane ligated stannylene

Nature Communications
Heavier group 14 carbene analogues, exhibiting transition-metal-like behavior, display remarkable capability for small molecule activation and coordination chemistry. However, their application in redox catalysis remains elusive. In this paper, we report
Zhuchunguang Liu, Zhijun Wang, Huan Mu, Yihan Zhou, Jiliang Zhou, Zhaowen Dong   +5 more
doaj   +1 more source

Green Chemistry Education: Recent Developments Green chemical processing ;, vol. 4./ Mark Anthony Benvenuto and Larry Kolopajlo.

, 2019
In English.Includes bibliographical references and index.Kolopajlo, Larry / Benvenuto, Mark -- Noce, Anthony M. -- Berger, Michael / Karod, Madeline / Goldfarb, Jillian L. -- Sadraei, S. Iraj / Onge, Brent St / Trant, John F.
Krikke James., Pothoof Justin., Kolopajlo Lawrence H.,, Berger Michael., Kohn Craig., Onge Brent S., Sliwinski Ben D., Ruprecht Michal., Benvenuto (Mark Anthony),, Sosnowski Ben M., Fitzgerald Polly R., Wathen Steven P., Goldfarb Jillian L., Kosmas Steven., Kovacs Dalila., Ause Robert., Mack Kristina., Noce Anthony., Patel Jay M., Sadraei S. Iraj., Trant John F., Karod Madeline., Mill Theodore., Tebes-Stevens Caroline.   +23 more
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