Results 111 to 120 of about 7,860,778 (297)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Melissa Aurisch of West Australian Ballet, November 2003 [picture] /

open access: yes, 2004
Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection 'avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core  

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Simon Dow in rehearsal for 'La Boheme', West Australian Ballet, 2004 [picture] /

open access: yes, 2004
Part of collection: Jon Green collection of photographs of Australian dancers and choreographers.; Title supplied by photographer.; Image from Jon Green's private collection, 'Avec attitude'.; Acquired in digital format; access copy available online ...
Green, Jon.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Telegram from Smith Green to his grandpa

open access: yes, 1945
Telegram from Smith Green to his grandpa, William Green, giving updates.1-3XZ4 10KM G 9 TOUR COLLECT = SAN FRANCISCO CALIF OCT 15 1945 813P= W M GREEN= BOX 426 BROKEN BOW OKLA = ARRIVED TODAY FEELING FINE HAVE SEEN FOLKS LOVE ...
Green, Smith Lowry
core  

Comrade Black Distribution [February 1998 catalogue]

open access: yes, 1998
The catalog of a D.I.Y. retail distributor of political and small press books and pamphlets. Started in 1996, CB Distribution is an effort to counter the homogeneity of political and artistic thought that dominates the mainstream media.
Comrade Black Distribution
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Identification of Inequities in Green Visibility and Ways to Increase Greenery in Neighborhoods: A Case Study of Wuhan, China

open access: yesApplied Sciences
The rapid increase in urban population density driven by urban development has intensified inequity in urban green space distribution. Identifying the causes of changes in green equity and developing strategies to improve urban greening are crucial for ...
Xiaohua Guo   +3 more
doaj   +1 more source

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