Results 231 to 240 of about 7,860,778 (297)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

53BP1 as a cofactor in the activation of the p53-family transcriptional program: A correlative multimodal microscopy approach. [PDF]

Sci Adv
Pelicci S, Furia L, Ciacci L, Gravina T, Pelicci PG, Dellino GI, Faretta M.   +6 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Influence of Drying Methods on Phytochemical Retention of <i>Moringa oleifera</i> Leaves and Green Synthesis of Zinc Oxide Nanoparticles Using the Optimal <i>Moringa oleifera</i> Leaf Extract. [PDF]

Food Sci Nutr
Rahman T, Siddikey F, Nabi MHB, Rayhan MA, Zzaman W.   +4 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Computational and experimental study of CuO-ZnO nanocomposite using the plant Peganum harmala L. and their antifungal, antibacterial applications. [PDF]

Discov Nano
Gul H, Zara F, Nasreen Z, Khan HA, Assad N, Khan MN, Khalid S, Adnan M, Kaplan A, Zaman A, Kifle D, Sindi AA, Tolah AM.   +12 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Sustainable synthesis of metallic nanoparticles and their potential biotechnological applications. [PDF]

Discov Nano
Ugale SV, Gaikwad SC, Bankar AV, Nawani N.   +3 more
europepmc   +1 more source

Comparative evaluation of machine learning algorithms for Maize Lethal Necrosis Disease detection under class imbalance. [PDF]

PLoS One
Wanyonyi M.
europepmc   +1 more source