Results 121 to 130 of about 1,756,591 (308)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

"Effect of p-aminosalicylic acid rare earth complex on aging resistance of natural rubber"

Hecheng xiangjiao gongye
Natural rubber (NR) vulcanizates were prepared using rare earth antioxidants, such as lanthanum aminosalicylate (PAS-La), cerium aminosalicylate (PAS-Ce), lanthanum and cerium aminosalicylate (PAS-La-Ce), and hindered phenolic antioxidant 2246 ...
"LIU Yong-gang1,2, HAO Wei2, LIU Zhao-gang2, WANG Xiao-li1, MA Sheng-mei1, ZHANG Shi-zhong1, ZHANG Feng-long1"
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Climate Effects of Carbon Taxes, Taking into Account Possible Other Future Climate Measures [PDF]

Increasing fuel extraction costs and global temperatures make it likely that in the medium-term future, technological or political measures against global warming will be implemented.
Habermacher, Florian, Kirchgässner, Gebhard   +1 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Tempering and modification of basic oxygen furnace slag with blast furnace slag: Mineral phase transformations and cementitious material enrichment mechanisms

Case Studies in Construction Materials
This study investigates the phase evolution and enrichment mechanism of the cementitious materials in a blend of blast furnace (BF) and basic oxygen furnace (BOF) slags.
Shuai Hao, Guoping Luo, Lin Wang, Shengli An, Yifan Chai, Wei Song   +5 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Quantitative evaluation on AlN transformation and volatilization of chlorides and fluorides in pyrometallurgical treatment for aluminum dross

Journal of Materials Research and Technology
Reaction characteristics in pyrometallurgical treatment for aluminum dross were studied qualitatively and quantitatively by thermal analysis. The transformation of aluminum nitride (AlN), volatilization of chlorides and fluorides in two kinds of dross ...
Rongbin Li, Jingjing Zhong, Mingzhuang Xie, Zhiwei Huang, Hongliang Zhao, Fengqin Liu   +5 more
doaj   +1 more source

Green Pulsed Electric Field-Assisted Extraction Method of Total Carotenoid Carrot Pulp Using Olive Oil as Solvent [PDF]

, 2014
Carrot (Daucus carrota L.) pulp as a by-product of carrot juice processing, containing a high content of total carotenoid. It was necessary for the extraction that can be used to other food products enriched by carotenoid.
Argo, B. D. (Bambang), Putranto, A. W. (Angky), Wijana, S. (Susinggih)   +2 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source