Results 121 to 130 of about 217,468 (292)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Optimization of the bi-oleothermal treatment process for wood preservation and fireproofing [PDF]
The bi-oleothermal© process (combination of oil and heat treatment) is a well mastered alternative method for wood protection. However, the fire behavior and resistance to decay of bi-oleothermally treated wood are not good enough to ensure performance ...
Alfos, Carine +5 more
core
Studies on the green and blue molds of Satsuma orange. VI.
In an inoculation experiment of P. digitatum against orange fruits, when phosphate buffer solutions of different pH, ranging from pH 2 to pH 8, were used as the media for spore suspension, affected area (macerated area) developed rapidly with the acidic spore suspension, while slow development was resulted with neutral to alkaline spore suspension ...
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Management of Green Mold Disease in White Button Mushroom (Agaricus bisporus) and Its Yield Improvement. [PDF]
Altaf S +14 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Research Progress on Heat Transfer Characteristics of Mold Flux Film in Continuous Casting Mold
The traditional mold flux is mainly composed of CaO and SiO2as the base material,supplemented by an appropriate amount of fluxing agent such as CaF2and the fluorine-free mold flux is to choose B2O3、TiO2and other suitable flux to replace CaF2to achieve ...
韩秀丽 +5 more
doaj
An active disordered medium able to lase is called a random laser (RL). We demonstrate random lasing due to inherent disorder in a dye circulated structured microfluidic channel.
B. N. Shivakiran Bhaktha +4 more
core +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

