Results 61 to 70 of about 16,475 (291)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Influence of Organizational Culture on Green IT Adoption: Study Literature

, 2019
Green IT (Information Technology) becomes one of the latest considerations to increase environmental sustainability and reduce the cost of Information Technology operation. However, the successful adoption of Green IT needs Green IT readiness measurement
Subriadi, Apol Pribadi; Department of Information Systems, Institut Teknologi Sepuluh Nopember, Dewi, Pramuditha Shinta; Department of Information Systems, Institut Teknologi Sepuluh Nopember   +1 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Role of Green Human Resource Management on Employee Behavior and Corporate Environmental Performance in Indonesian Sharia Banks

Shirkah
The growing number of companies focusing on environmental preservation and the limited literature on green human resource management in the Islamic banking industry make this an intriguing topic for deeper research.
Rosya Mawaddah Susanto, Siswanto Siswanto, Yayuk Sri Rahayu   +2 more
doaj   +1 more source

“GREEN” HRM IN PURSUIT OF SUSTAINABLE COMPETITIVE ADVANTAGE

AICEI Proceedings, 2020
The recent years have witnessed the emergence of “Green” Human Resource Management (HRM) as one of the main strategic concepts which aims to shape employee behaviour to help organizations achieve a sustainable competitive advantage.
Snezhana Hristova, Dusica Stevceska- Srbinovska   +1 more
doaj   +1 more source

The effect of green human resources on green social capital with the mediating role of green organizational culture and environmental knowledge [PDF]

مطالعات مدیریت توسعه سبز
IntroductionSome organizational managers believe that investing in environmental issues is unnecessary (Wang, 2019: 667). Environmental challenges can be considered as opportunities to gain green social capital (Xuemei et al., 2022: 100).
Mojtaba Farokhi, Zeynab Amiri, Mohammad mahdi Faramarzi   +2 more
doaj   +1 more source

Investigating the Emergence of Employee Green Behavior Through Green Organizational Culture and Organizational Commitment

INSAN Jurnal Psikologi dan Kesehatan Mental
Research on employee green behavior is increasing as companies are becoming more aware of environmental protection. The implementation of green culture is thought to help organizations in shaping green behavior among employees, but past researches show inconsistency regarding the significant impact of green organizational culture on employee green ...
Naila Cahayani Putri, null Fajrianthi
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The impact of the prevailing organizational culture on the adoption of green marketing in chemical-industry companies in three Arab states in west Asia [PDF]

The objective of this study was to investigate the impact of the prevailing organizational culture on the adoption of green marketing in chemical-industry companies in three countries: Syria, Kuwait and Jordan. The research used a survey methodology.
Nahla Al-Rifai, Tareq N. Hashem
core