Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Ecophysiological study of green microalgae isolated from the grit crust of the Atacama Desert. [PDF]
Glaser K +4 more
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
TiO<sub>2</sub>-coated guided-mode resonance gratings for polarization-selective green light filtering. [PDF]
Aslam K, Mushtaq N, Chai Y, Kang G.
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Quantifying and mapping uncertainty in urban sentiment prediction: a combined approach with entropy and SHAP explanations. [PDF]
Betco I, Ribeiro AI, Viana CM, Rocha J.
europepmc +1 more source
GREEN VALUE FOR GREEN MARKETING: REVOLUTION OF PAST VALUE SYSTEM
openaire
Comparative efficacy of green exercise versus indoor exercise for depression and anxiety: a systematic review and network meta-analysis. [PDF]
Liang Y, Wei DY, Min S.
europepmc +1 more source
Cytokinin-GLK regulatory module promotes the acquisition of photosynthetic activity and cell cycle re-entry in a green-flower mutant of <i>Narcissus tazetta</i> var. <i>chinensis</i>. [PDF]
Zhang WH +8 more
europepmc +1 more source

