Results 101 to 110 of about 751,000 (286)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
'BioNessie(G) - a grid enabled biochemical networks simulation environment [PDF]
, 2008 The simulation of biochemical networks provides insight and understanding about the underlying biochemical processes and pathways used by cells and organisms.
Liu, X +5 more
core
Ambient stable large-area flexible organic solar cells using silver grid hybrid with vapor phase polymerized poly (3,4-Ethylenedioxythiophene) cathode [PDF]
, 2015 The presence of PSS in solution processed high conducting polymer PEDOT:PSS (PH1000) limits the reliability and lifetime of organic photovoltaic devices due to its acidic and hygroscopic nature.
Wu, D(吴丹) +12 more
core +1 more source
Grid Cells Lose Coherence in Realistic Environments [PDF]
, 2021 Spatial cognition in naturalistic environments, for freely moving animals, may pose quite different constraints from that studied in artificial laboratory settings.
Treves, A. +9 more
core +1 more source
Grid Cells Encode Local Positional Information. [PDF]
Curr Biol, 2017 The brain has an extraordinary ability to create an internal spatial map of the external world [1]. This map-like representation of environmental surroundings is encoded through specific types of neurons, located within the hippocampus and entorhinal ...
Ismakov R +3 more
europepmc +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
BioNessie - a grid enabled biochemical networks simulation environment [PDF]
, 2008 The simulation of biochemical networks provides insight and understanding about the underlying biochemical processes and pathways used by cells and organisms.
Gu, Xu +11 more
core
Advanced Engineering Materials, EarlyView.A combined finite element and phase‐field approach predicts the evolution of microstructure during the directional solidification of Ni‐based superalloys. The model reveals how withdrawal rate, temperature gradient, and wall thickness control the dendrite spacing, highlighting the strong effect of surface regions in thin sections where dendrite growth ...
Sean Böhm +3 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed +6 more
wiley +1 more source
Shedding light on stellate cells
eLife, 2018 The relationship between grid cells and two types of neurons found in the medial entorhinal cortex has been clarified.
Andrew S Alexander, Michael E Hasselmo
doaj +1 more source