Results 71 to 80 of about 12,675,276 (305)
GABAA Receptor Subunit α3 in Network Dynamics in the Medial Entorhinal Cortex
Frontiers in Systems Neuroscience, 2019 Layer II of the medial entorhinal cortex (MEC LII) contains the largest number of spatially modulated grid cells and is one of the first regions in the brain to express Alzheimer’s disease (AD)-related pathology.
Nina Berggaard +2 more
doaj +1 more source
, 2009 Let $S$ be a set of $n^2$ symbols. Let $A$ be an $n\times n$ square grid with each cell labeled by a distinct symbol in $S$. Let $B$ be another $n\times n$ square grid, also with each cell labeled by a distinct symbol in $S$. Then each symbol in $S$ labels two cells, one in $A$ and one in $B$. Define the \emph{combined distance} between two symbols in $
Jiang, Minghui, Tejada, Pedro J.
openaire +2 more sources
Functional properties of stellate cells in medial entorhinal cortex layer II
eLife, 2018 Layer II of the medial entorhinal cortex (MEC) contains two principal cell types: pyramidal cells and stellate cells. Accumulating evidence suggests that these two cell types have distinct molecular profiles, physiological properties, and connectivity ...
David C Rowland +6 more
doaj +1 more source
Evaluating State Space Discovery by Persistent Cohomology in the Spatial Representation System
Frontiers in Computational Neuroscience, 2021 Persistent cohomology is a powerful technique for discovering topological structure in data. Strategies for its use in neuroscience are still undergoing development.
Louis Kang +3 more
doaj +1 more source
An oscillatory interference model of grid cell firing [PDF]
, 2007 We expand upon our proposal that the oscillatory interference mechanism proposed for the phase precession effect in place cells underlies the grid-like firing pattern of dorsomedial entorhinal grid cells (O'Keefe and Burgess (2005) Hippocampus 15:853-866)
Barry, C, Burgess, N, O'Keefe, J
core +1 more source
Membrane potential dynamics of grid cells [PDF]
Nature, 2013 During navigation, grid cells increase their spike rates in firing fields arranged on a markedly regular triangular lattice, whereas their spike timing is often modulated by theta oscillations. Oscillatory interference models of grid cells predict theta amplitude modulations of membrane potential during firing field traversals, whereas competing ...
Domnisoru, Cristina +2 more
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
W-band waveguide-packaged InP HEMT reflection grid amplifier [PDF]
, 2006 This letter presents a 79-GHz broadband reflection-type grid amplifier using spatial power combining to combine the power of 64 unit cells. Each unit cell uses a two-stage cascade configuration with InP HEMTs arranged as a differential pair.
Cheung, Chun-Tung +3 more
core +1 more source
Modeling Grid Cell Distortions with a Grid Cell Calibration Mechanism
Cyborg and Bionic SystemsThe medial entorhinal cortex of rodents is known to contain grid cells that exhibit precise periodic firing patterns based on the animal’s position, resulting in a distinct hexagonal pattern in space. These cells have been extensively studied due to their potential to unveil the navigational computations that occur within the mammalian brain and ...
Daniel Strauß +4 more
openaire +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source