The effect of varying water volumes on in vivo dissolution and gastric emptying of highly soluble caffeine and lesser soluble theobromine containing capsules. [PDF]
Großmann L +7 more
europepmc +1 more source
Endogenous Protein Tagging in Postmitotic Neurons via Lentiviral and Adeno‐associated Virus Delivery
Abstract This protocol describes a method for endogenous protein tagging in postmitotic primary neurons using homology‐independent targeted integration (HITI), a CRISPR/Cas9‐based approach that exploits non‐homologous end joining (NHEJ). Unlike homology‐directed repair (HDR), HITI does not require cell division, making it uniquely suited for ...
Lorena Benedetti +3 more
wiley +1 more source
Combining paleoecology and modeling to explore cascading disturbances in forest ecosystems
Climate‐induced cascading disturbance interactions pose a major challenge to the sustainable provision of forest ecosystem services to society. Developing a deeper understanding and enhanced capacity to simulate these interactions is essential for identifying disturbance‐induced tipping points in forest ecosystems, and for improving management in ...
Cécile C. Remy +6 more
wiley +1 more source
Thermal septotomy complications and management of residual septum visceral ostial occlusions. [PDF]
Shields C +5 more
europepmc +1 more source
Abstract Agriculture and urban areas are the dominant forms of human land use globally and contribute to declines in avian biodiversity and the homogenization of avian communities relative to natural landscapes. However, how avian communities differ between agricultural and urbanized landscapes remains unclear. As human land use expands and intensifies,
R. E. Bockrath +4 more
wiley +1 more source
Understanding Practitioner Comfort and Educational Priorities for Safe Opioid Prescribing: A Repeated Cross-Sectional Study. [PDF]
Lai B +4 more
europepmc +1 more source
Rethinking Environmental Impact Assessment for nature positive development
Achieving “nature positive” development within existing regulatory frameworks will be challenging. Halting and reversing biodiversity loss requires protection, restoration, and enhancement of ecosystems alongside a fundamental shift in how biodiversity is valued and quantifiable improvements are assessed.
Holly Kirk +5 more
wiley +1 more source
Neonatal diethylstilbestrol exposure disrupts uterine epithelial apical-basal polarity and partial EMT state. [PDF]
Bainbridge RE +4 more
europepmc +1 more source
Stable but Transient—Episodic Sensitivity in a Buffered German Karst Headwater Stream
Baseline carbonate chemistry revealed coherent, degassing‐controlled patterns across the stream. Although warm low‐flow and rewetting periods temporarily increased system variability, carbonate buffering persisted (I). In addition, gas transfer and local hydromorphology decoupled CO2 evasion from pCO2 in a spring‐fed karst headwater stream (II ...
Christina M. Schubert +3 more
wiley +1 more source

