Results 1 to 10 of about 35,246 (224)

GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action [PDF]

Frontiers in Endocrinology, 2021
The glucagon-like peptide-1 receptor (GLP-1R) is a G-protein-coupled receptor (GPCR) whose activation results in suppression of food intake and improvement of glucose metabolism. Several receptor interacting proteins regulate the signaling of GLP-1R such
Seunghun P. Lee, Jenson Qi, Guozhang Xu, Matthew M. Rankin, James Littrell, June Zhi Xu, Ivona Bakaj, Alessandro Pocai   +7 more
doaj   +3 more sources

Intracellular and Extracellular Roles of Granzyme K

Frontiers in Immunology, 2021
Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune system. Granzyme K (GrK) has been only limitedly characterized and knowledge on its molecular functions is emerging.
Annemieke C. Bouwman, Kim R. van Daalen, Sandra Crnko, Toine ten Broeke, Niels Bovenschen, Niels Bovenschen   +5 more
doaj   +1 more source

Pengurangan emisi gas rumah kaca pada perkebunan kelapa sawit dengan pendekatan life cycle assessment

Journal of Natural Resources and Environmental Management, 2021
Pertumbuhan perkebunan kelapa sawit di Indonesia mengalami peningkatan yang cukup pesat. Dampak negatif yang ditimbulkan akibat pertumbuhan perkebunan kelapa sawit ini adalah kerusakan lingkungan dan peningkatan emisi gas rumah kaca (GRK). Penelitian ini
Danang Harimurti
doaj   +1 more source

Granzyme K activates protease-activated receptor-1. [PDF]

PLoS ONE, 2011
Granzyme K (GrK) is a trypsin-like serine protease that is elevated in patients with sepsis and acute lung inflammation. While GrK was originally believed to function exclusively as a pro-apoptotic protease, recent studies now suggest that GrK may ...
Dawn M Cooper, Dmitri V Pechkovsky, Tillie L Hackett, Darryl A Knight, David J Granville   +4 more
doaj   +1 more source

Extracellular Granzyme K Modulates Angiogenesis by Regulating Soluble VEGFR1 Release From Endothelial Cells

Frontiers in Oncology, 2021
Angiogenesis is crucial for normal development and homeostasis, but also plays a role in many diseases including cardiovascular diseases, autoimmune diseases, and cancer.
Shuang Li, Christian G. M. van Dijk, Jan Meeldijk, Helena M. Kok, Isabelle Blommestein, Annick L. F. Verbakel, Marit Kotte, Roel Broekhuizen, Miangela M. Laclé, Roel Goldschmeding, Caroline Cheng, Niels Bovenschen, Niels Bovenschen   +12 more
doaj   +1 more source

Metode Pembelajaran Mesin untuk Memprediksi Emisi Manure Management

Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2022
Indonesia berkomitmen menurunkan emisi gas rumah kaca (GRK) melalui skema nationally determined contribution (NDC). Target yang hendak dicapai untuk menurunkan emisi GRK yaitu 29% melalui skema business as usual (BAU) atau 41% dengan bantuan ...
Widi Hastomo, Nur Aini, Adhitio Satyo Bayangkari Karno, L.M. Rasdi Rere   +3 more
doaj   +1 more source

Photocatalytic Isomerization of (E)-Anethole to (Z)-Anethole

Molecules, 2022
Natural product (E)-anethole was isomerized to (Z)-anethole in a photocatalytic reaction. For this purpose, a self-designed cheap photoreactor was constructed.
Marvin Korff, Tiffany O. Paulisch, Frank Glorius, Nikos L. Doltsinis, Bernhard Wünsch   +4 more
doaj   +1 more source

Pemetaan Potensi Energi Terbarukan Desa Belum Berlistrik Di Papua Barat Guna Meningkatkan Elektrifikasi Dan Reduksi Emisi Gas Rumah Kaca

Dinamika Rekayasa, 2022
Pemetaan potensi energi terbarukan penting dilakukan untuk mengetahui potensi energi terbarukan dan potensi reduksi emisi gas rumah kaca (GRK) desa belum berlistrik di Provinsi Papua Barat yang berjumlah 29 desa.
Elias Kondorura Bawan, Ahmad Fakhrur Rozi   +1 more
doaj   +1 more source

G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D₂ Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

Biomolecules, 2023
The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to regulate important physiological processes, such as movement, reward circuitry, emotion, and cognition.
Marta Sánchez-Soto, Noelia M. Boldizsar, Kayla A. Schardien, Nora S. Madaras, Blair K. A. Willette, Laura R. Inbody, Christopher Dasaro, Amy E. Moritz, Julia Drube, Raphael S. Haider, R. Benjamin Free, Carsten Hoffman, David R. Sibley   +12 more
doaj   +1 more source

G protein-coupled receptor kinase-2 (GRK-2) controls exploration through neuropeptide signaling in Caenorhabditis elegans.

PLoS Genetics, 2023
Animals alter their behavior in manners that depend on environmental conditions as well as their developmental and metabolic states. For example, C. elegans is quiescent during larval molts or during conditions of satiety.
Kristen Davis, Christo Mitchell, Olivia Weissenfels, Jihong Bai, David M Raizen, Michael Ailion, Irini Topalidou   +6 more
doaj   +1 more source