Results 21 to 30 of about 35,246 (224)
GRKs as Key Modulators of Opioid Receptor Function [PDF]
Cells, 2020 Understanding the link between agonist-induced phosphorylation of the mu-opioid receptor (MOR) and the associated physiological effects is critical for the development of novel analgesic drugs and is particularly important for understanding the mechanisms responsible for opioid-induced tolerance and addiction.
Laura Lemel +2 more
openaire +3 more sources
Relative Gottlieb Groups of Embeddings between Complex Grassmannians
International Journal of Mathematics and Mathematical Sciences, 2021 Let Grk,n be the complex Grassmann manifold of k-linear subspaces in ℂn. We compute rational relative Gottlieb groups of the embedding i:Grk,n⟶Grk,n+r and show that the G-sequence is exact if r≥kn−k.
J. B. Gatsinzi
doaj +1 more source
The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs [PDF]
Journal of Biological Chemistry, 2006 We describe the 2.6-A crystal structure of human G protein-coupled receptor kinase (GRK)-6, a key regulator of dopaminergic signaling and lymphocyte chemotaxis. GRK6 is a member of the GRK4 subfamily of GRKs, which is represented in most, if not all, metazoans.
David T, Lodowski +3 more
openaire +2 more sources
Gallai-Ramsey Numbers for Rainbow S3+S_3^ + and Monochromatic Paths
Discussiones Mathematicae Graph Theory, 2022 Motivated by Ramsey theory and other rainbow-coloring-related problems, we consider edge-colorings of complete graphs without rainbow copy of some fixed subgraphs.
Li Xihe, Wang Ligong
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Differential Regulation of GPCRs—Are GRK Expression Levels the Key?
Frontiers in Cell and Developmental Biology, 2021 G protein-coupled receptors (GPCRs) comprise the largest family of transmembrane receptors and their signal transduction is tightly regulated by GPCR kinases (GRKs) and β-arrestins.
Edda S. F. Matthees +3 more
doaj +1 more source
Sign variation, the Grassmannian, and total positivity [PDF]
, 2015 The totally nonnegative Grassmannian is the set of k-dimensional subspaces V of R^n whose nonzero Pluecker coordinates all have the same sign. Gantmakher and Krein (1950) and Schoenberg and Whitney (1951) independently showed that V is totally ...
Karp, Steven N.
core +4 more sources
Jurnal Ilmiah Ilmu-Ilmu Peternakan, 2019 Gas rumah kaca (GRK) dalam bentuk CH4 dan N2O memberikan kontribusi terhadap pemanasan global. Sektor pertanian menyumbang 10-12% dari total GRK antropogenik dari gas CH4 dan N2O.
Hutwan Syarifuddin +2 more
doaj +3 more sources
PLoS ONE, 2013 In the Drosophila oocyte, gurken (grk) mRNA encodes a secreted TGF-α signal that specifies the future embryonic dorso-ventral axes by altering the fate of the surrounding epithelial follicle cells.
Suzanne M McDermott, Ilan Davis
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Fantastische Technik im Mittelalter? Zu (Glücks-)Rädern in zwei mittelhochdeutschen Artusromanen
Zeitschrift für Fantastikforschung, 2020 Recent works in the field of German medieval literature argue that the category of ›the fantastic‹ needs to be defined in demarcation to the medieval category of ›the marvelous‹, and, thus, the focus of text analyses should lay on forms and functions of ›
Hanna Myriam Häger
doaj +2 more sources
Hepatology, EarlyView., 2022 Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid +20 more
wiley +1 more source