Results 21 to 30 of about 30,272 (208)

Design and analytical validation of a duplex PCR for Ehrlichia and Rickettsia detection in ticks

Revista Colombiana de Ciencias Pecuarias, 2018
Background: Ehrlichia and Rickettsia are two major rickettsial genera transmitted by ticks that affect a number of wild and domestic animal species and human populations around the world.
Juan C. Pérez Pérez, Carolina Montoya Ruiz, Esteban Arroyave Sierra, Luis E. Paternina, Juan D. Rodas   +4 more
doaj   +1 more source

Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]

, 2019
Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano, De Zutter, Lieven, Garmyn, An, Haesebrouck, Freddy, Heyndrickx, Marc, Martel, An, Pasmans, Frank, Van Rysselberghe, Nathalie, Vandeputte, Jasmien   +8 more
core   +1 more source

In silico identification of functional divergence between the multiple groEL gene paralogs in Chlamydiae

BMC Evolutionary Biology, 2007
Background Heat-shock proteins are specialized molecules performing different and essential roles in the cell including protein degradation, folding and trafficking.
Fares Mario A, McNally David
doaj   +1 more source

Environmental stress responses in Lactococcus lactis [PDF]

, 1999
Bacteria can encounter a variety of physical conditions during their life. Bacterial cells are able to survive these (often adverse) conditions by the induction of specific or general protection mechanisms. The lactic acid bacterium Lactococcus lactis is
Kok, Jan,, Sanders, Jan Willem,, Venema, Gerard,   +2 more
core   +3 more sources

Identifying protein stabilizing ligands using GroEL [PDF]

Biopolymers, 2009
AbstractOver the past 5 years, it has become increasingly apparent to researchers that the initial promise and excitement of using gene replacement therapies to ameliorate folding diseases are still far from being broadly or easily applicable. Because a large number of human diseases are protein folding diseases (∼30 to 50%), many researchers now ...
Subhashchandra, Naik, Inamul, Haque, Nick, Degner, Boris, Kornilayev, Gregory, Bomhoff, Jacob, Hodges, Ara-Azad, Khorassani, Hiroo, Katayama, Jill, Morris, Jeffery, Kelly, John, Seed, Mark T, Fisher   +11 more
openaire   +2 more sources

Chaperonin GroEL Reassembly: An Effect of Protein Ligands and Solvent Composition

Biomolecules, 2014
Chaperonin GroEL is a complex oligomeric heat shock protein (Hsp60) assisting the correct folding and assembly of other proteins in the cell. An intriguing question is how GroEL folds itself.
Nataliya Ryabova, Victor Marchenkov, Nina Kotova, Gennady Semisotnov   +3 more
doaj   +1 more source

In Vivo Incorporation of Photoproteins into GroEL Chaperonin Retaining Major Structural and Functional Properties

Molecules, 2023
The incorporation of photoproteins into proteins of interest allows the study of either their localization or intermolecular interactions in the cell.
Victor Marchenkov, Tanya Ivashina, Natalia Marchenko, Natalya Ryabova, Olga Selivanova, Alexander Timchenko, Hiroshi Kihara, Vladimir Ksenzenko, Gennady Semisotnov   +8 more
doaj   +1 more source

Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]

, 2018
Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J, Cobb, Brian A, Hiyoshi, Hirotaka, Lock, Gabriel, Raffatellu, Manuela, Saechao, Cheng, Wangdi, Tamding   +6 more
core   +2 more sources

Probing the functional mechanism of Escherichia coli GroEL using circular permutation. [PDF]

PLoS ONE, 2011
BACKGROUND: The Escherichia coli chaperonin GroEL subunit consists of three domains linked via two hinge regions, and each domain is responsible for a specific role in the functional mechanism.
Tomohiro Mizobata, Tatsuya Uemura, Kazuhiro Isaji, Takuma Hirayama, Kunihiro Hongo, Yasushi Kawata   +5 more
doaj   +1 more source

GroEL/ES inhibitors as potential antibiotics [PDF]

Bioorganic & Medicinal Chemistry Letters, 2016
We recently reported results from a high-throughput screening effort that identified 235 inhibitors of the Escherichia coli GroEL/ES chaperonin system [Bioorg. Med. Chem. Lett.2014, 24, 786]. As the GroEL/ES chaperonin system is essential for growth under all conditions, we reasoned that targeting GroEL/ES with small molecule inhibitors could be a ...
Sanofar Abdeen, Nilshad Salim, Najiba Mammadova, Corey M. Summers, Rochelle Frankson, Andrew J. Ambrose, Gregory G. Anderson, Peter G. Schultz, Arthur L. Horwich, Eli Chapman, Steven M. Johnson   +10 more
openaire   +2 more sources