Results 51 to 60 of about 96,261 (266)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Gross motor developmental dysfunctional outcomes in infantile and toddler pediatric intensive care unit survivors

BMC Pediatrics, 2019
Background Increasing studies have focused on motor function/dysfunction in PICU survivors; however, most studies have focused on adults and older children.
Chun-Feng Yang, Yang Xue, Jun-Yan Feng, Fei-Yong Jia, Yu Zhang, Yu-Mei Li   +5 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records From an Integrated Health System

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the frequency and timing of physician referrals to physical therapists (PTs) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source

The Effect of Perceptual – Motor Experience on Motor Development Quotient of Fine and Gross Motor Skills in 5-8-Month-Old Infants [PDF]

رشد و یادگیری حرکتی ورزشی, 2010
The purpose of this study was to investigate the effect of perceptual – motor experience on motor development quotient of fine and gross motor skills in infants.
Alireza Farsi, Behroz Abdoli, Maryam Kaviani, Akram Kaviani   +3 more
doaj  

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

Arthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan, Catherine M. Guly, Gabriele Simonini, Stuart Y. Keller, Priyanka Sen, Thorsten Holzkaemper, Joana Araújo, Pierre Quartier   +7 more
wiley   +1 more source

Elaboration of the Environmental Stress Hypothesis – Results from a population-based 6-year follow-up

Frontiers in Psychology, 2016
The aim of this paper was to contribute to the elaboration of the Environmental Stress Hypothesis framework by testing eight hypotheses addressing the direct impact of gross motor coordination problems in elementary-school on selected physical ...
Matthias Wagner, Darko Jekauc, Annette Worth, Alexander Woll   +3 more
doaj   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Training Mothers to Improve Gross Motor Skills in Children With Cerebral Palsy: A Randomized Controlled Trial

Iranian Rehabilitation Journal, 2019
Objectives: The present study examined the effect of home-based handling training of mothers on the improvement of gross motor function of children with Cerebral Palsy (CP).
Sahar Johari, Mina Ahmadi Kahjoogh, Fatemeh Sanei, Naser Havaei, Mostafa Daemi   +4 more
doaj  

Risk factors of gross and fine motor development delays in children living in institution care

Acta Psychologica
Background: Growth delays, including gross and fine motor development, were commonly observed in children living in child residential facilities. However, there is limited data on the risk factors for delayed motor function in these children.
Benjaporn Srinithiwat, Patcharapun Sarisuta, Tachakorn Angsanu, Phimphon Thuayta, Kittisak Sawanyawisuth   +4 more
doaj   +1 more source