Results 71 to 80 of about 962,375 (304)

Observation of magnetic fragmentation in spin ice [PDF]

open access: yes, 2016
Fractionalised excitations that emerge from a many body system have revealed rich physics and concepts, from composite fermions in two-dimensional electron systems, revealed through the fractional quantum Hall effect, to spinons in antiferromagnetic ...
Balakrishnan, G.   +9 more
core   +4 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Ground ice map of Canada

open access: yes, 2020
This Open File presents new national-scale mapping of ground ice conditions in Canada. The mapping depicts a first-order estimate of the combined volumetric percentage of excess ice in the top 5 m of permafrost from segregated, wedge, and relict ice. The estimates for the three ice types are based on modelling by O'Neill et al.
H B O'Neill, S A Wolfe, C Duchesne
openaire   +1 more source

Late-Pleistocene Syngenetic Permafrost in the CRREL Permafrost Tunnel, Fox, Alaska [PDF]

open access: yes, 2008
contributing authors: Bjella, K.L., Bray, M.T., Collins, C.M., Douglas, T.A., Fortier, D., French, H.M., Kanevskiy, M.Z., Shur, Y.L.Late-Pleistocene syngenetic permafrost exposed in the walls and ceiling of the CRREL permafrost tunnel consists of ice-and
French, H.M.   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Excess Ground Ice Profiles in Continuous Permafrost Mapped From InSAR Subsidence

open access: yesWater Resources Research
Excess ground ice formation and melt drive surface heave and settlement, and are critical components of the water balance in Arctic soils. Despite the importance of excess ice for the geomorphology, hydrology and biogeochemistry of permafrost landscapes,
S. Zwieback   +5 more
doaj   +1 more source

The ground ice melting has accelerated the lake expansion in the hinterland of the permafrost region on the Qinghai-Tibet Plateau

open access: yesJournal of Hydrology: Regional Studies
Study region: The Zonag Lake-Yanhu Lake basin on the Qinghai-Tibet Plateau (QTP). Study focus: The melting of ground ice near the permafrost table is an important factor leading to the lake expansion on the QTP.
Shibo Liu   +9 more
doaj   +1 more source

GROUND PENETRATING RADAR DATA INTERPRETATION USING ELECTROMAGNETIC FIELD ANALYSIS FOR SEA ICE THICKNESS MEASUREMENT [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Observation of sea ice thickness by remote sensing is one of key issues to understand an effect of global warming. However, ground truth must be necessary to discuss this kind of approach.
M. Matsumoto   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Predictive Skill of a Remote Sensing-Based Machine Learning Model for Ice Wedge and Visible Ground Ice Identification in Western Arctic Canada

open access: yesRemote Sensing
Fine-scale maps of ground ice and related surface features are critical for permafrost-related modelling and management. However, such maps are lacking across almost the entire Arctic.
Qianyu Chang   +2 more
doaj   +1 more source

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