Results 51 to 60 of about 18,103 (261)
Building Deformation Prediction Based on Ground Surface Settlements of Metro-Station Deep Excavation
Advances in Civil Engineering, 2018 Building deformations are not only closely related to the distance from the building to metro-station excavation but also related to the relative positions of the building and metro-station excavation.
Dapeng Li, Changhong Yan
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Doboku Gakkai Ronbunshuu F, 2007 兵庫県北部の豊岡盆地では，沖積粘性土地盤が厚く堆積しており，盆地の中央を北上する1級河川である円山川の築堤工事に際しても，市街地周辺では，近接している民家に対して，築堤盛土に伴う周辺地盤沈下の抑制が大きな課題とされてきた．本論文では，対策工として，深層混合処理工（CDM工法）を選定し，対策工による沈下抑制効果の予測および試験盛土の動態観測結果との対比により，予測計算の有効性および対策工による沈下抑制効果が高いことが確認できた．この結果，対策工の設計に際して，改良深度，改良幅，改良強度と周辺家屋の傾斜角が関連する対策工の最適化設計チャートについて新たに提案するとともに，対策工の施工時の変位抑制のために施工した緩衝孔の効果について論じる．
TSUBOTA, Kuniharu +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Applied SciencesConstruction-induced mutual disturbance exerts a substantial influence on the ground settlement of double-line tunnels, and the ground settlement of double-line tunnels differs under varying excavation conditions.
Zhiheng Jiang, Yuke Wang
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Settlement characteristics of major infrastructures in Shanghai [PDF]
Proceedings of the International Association of Hydrological Sciences, 2015 Critical infrastructures in Shanghai have undergone uneven settlement since their operation, which plays an important role in affecting the security of Shanghai.
X. Jiao +5 more
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FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Advances in Civil Engineering, 2018 A case study of monitoring and analysis of ground settlement caused by tunnelling of stacked twin tunnels for underground metro line construction through the densely populated area using the slurry pressure-balanced TBM is presented.
Hyunku Park +3 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source