Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
A K‐band eight‐element reconfigurable phased‐array receiver with high Tx‐band rejection
IET Microwaves, Antennas & PropagationA K‐band eight‐element phased‐array receiver is proposed, featuring a reconfigurable beam count and high Tx‐band rejection, tailored for satellite communication applications. By precisely designing the inter‐stage and output matching networks of the four‐
Zhuoheng Xie +10 more
doaj +1 more source
Spin-3/2 Ising model on a two-layer Bethe lattice with FM/AFM interactions
Condensed Matter Physics, 2009 Two-layer Bethe lattice whose lattice sites are occupied with spin-3/2 atoms is solved exactly by using the recursion relations in a pairwise approach for given coordination numbers q=3,4 and 6 with equal external magnetic fields acting on the layers ...
E. Albayrak, A. Yigit
doaj +1 more source
Exact Bond Ordered Ground State for the Transition between the Band and the Mott Insulator [PDF]
, 2004 Cristian D. Batista, A. A. Aligia
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Ground-state energies, densities and momentum distributions in closed-shell nuclei calculated within a cluster expansion approach and realistic interactions [PDF]
, 2005 Massimiliano Alvioli +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Spatial entanglement entropy in the ground state of the Lieb-Liniger model [PDF]
, 2016 Chris M. Herdman +3 more
openalex +1 more source
Polarization dependent photoemission as a probe of the magnetic ground state in the layered ferromagnet VI3 [PDF]
, 2022 Derek Bergner +13 more
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source