Results 91 to 100 of about 142,338 (258)
Ground-state solutions of a Hartree–Fock type system involving critical Sobolev exponent
Electronic Journal of Qualitative Theory of Differential EquationsIn this paper, ground-state solutions to a Hartree–Fock type system with a critical growth are studied. Firstly, instead of establishing the local Palais–Smale (P.-S.) condition and estimating the mountain-pass critical level, a perturbation method is ...
Xiaoli Zhu, Zushun Min
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Ground state solutions for asymptotically periodic Schrodinger-Poisson systems in R^2
Electronic Journal of Differential Equations, 2018 This article concerns the planar Schrodinger-Poisson system $$\displaylines{ -\Delta u+V(x)u+\phi u=f(x,u), \quad x\in \mathbb{R}^2,\cr \Delta \phi= u^2, \quad x\in \mathbb{R}^2, } $$ where V(x) and f(x, u) are periodic or asymptotically periodic in
Jing Chen, Sitong Chen, Xianhua Tang
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Ground state solutions for Hamiltonian elliptic system with sign-changing potential
Electronic Journal of Differential Equations, 2017 This article concerns the Hamiltonian elliptic system $$\displaylines{ -\Delta u +V(x)u=H_{v}(x, u, v),\quad x\in \mathbb{R}^N, \cr -\Delta v +V(x)v=H_{u}(x, u, v),\quad x\in \mathbb{R}^N, \cr u(x)\to 0,\quad v(x)\to 0, \quad \text{as } |x|\to ...
Wen Zhang, Xiaoliang Xie, Heilong Mi
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source