Results 81 to 90 of about 142,338 (258)

Ground state solutions for Hamiltonian systems with double exponential growth

open access: yesBoundary Value Problems
This study explores the existence of ground state solutions for a Hamiltonian elliptic system in the whole plane R 2 $\mathbb{R}^{2}$ , involving double exponential growth nonlinearities, which are given by the Trudinger–Moser inequalities in weighted ...
Yony Raúl Santaria Leuyacc
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Ground state solutions for magnetic Schrödinger equations with polynomial growth

open access: yesAdvances in Nonlinear Analysis
In this article, we investigate the following nonlinear magnetic Schrödinger equations: (−i∇+A(x))2u+V(x)u=f1(x,∣v∣2)v,(−i∇+A(x))2v+V(x)v=f2(x,∣u∣2)u,\left\{\begin{array}{l}{\left(-i\nabla +A\left(x))}^{2}u+V\left(x)u={f}_{1}\left(x,{| v| }^{2})v ...
Wu Yan, Chen Peng
doaj   +1 more source

Symmetry and concentration behavior of ground state in axially symmetric domains

open access: yesAbstract and Applied Analysis, 2004
We let Ω(r) be the axially symmetric bounded domains which satisfy some suitable conditions, then the ground-state solutions of the semilinear elliptic equation in Ω(r) are nonaxially symmetric and concentrative on one side.
Tsung-Fang Wu
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Ground state solutions for quasilinear Schrodinger equations with periodic potential

open access: yesElectronic Journal of Differential Equations, 2020
This article concerns the quasilinear Schrodinger equation $$\displaylines{ -\Delta u-u\Delta (u^2)+V(x)u=K(x)|u|^{2\cdot2^*-2}u+g(x,u),\quad x\in\mathbb{R}^N, \cr u\in H^1(\mathbb{R}^N),\quad u>0, }$$ where V and K are positive, continuous and ...
Jing Zhang, Chao Ji
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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