Results 101 to 110 of about 2,722,864 (361)

Asymptotic Behavior of Ground State Radial Solutions for -Laplacian Problems

open access: yesJournal of Mathematics, 2013
Let , we take up the existence, the uniqueness and the asymptotic behavior of a positive continuous solution to the following nonlinear problem in , , , , where , is a positive differentiable function in and is a positive continuous function in such ...
Sonia Ben Othman   +2 more
doaj   +1 more source

Ground state sign-changing solutions for Kirchhoff equations with logarithmic nonlinearity

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2019
In this paper, we study Kirchhoff equations with logarithmic nonlinearity: \begin{equation*} \begin{cases} -(a+b\int_\Omega|\nabla u|^2)\Delta u+ V(x)u=|u|^{p-2}u\ln u^2, & \mbox{in}\ \Omega,\\ u=0,& \mbox{on}\ \partial\Omega, \end{cases} \end{equation*}
Lixi Wen, Xianhua Tang, Sitong Chen
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Existence and multiplicity of positive solutions for indefinite semilinear elliptic problems in R^N

open access: yesElectronic Journal of Differential Equations, 2014
In this article, we study a class of indefinite semilinear elliptic problems in R^N. By using the fibering maps and studying some properties of the Nehari manifold, we obtain the existence and multiplicity of positive solutions.
Yi-Hsin Cheng, Tsung-Fang Wu
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

On Optimal Hardy Inequalities in Cones

open access: yesBruno Pini Mathematical Analysis Seminar, 2014
For a given subcritical Schrödinger operator in a cone in ℝn with a given Hardy potential corresponding to the distance to the boundary of the cone, we present an explicit optimal Hardy-type improvement.
Baptiste Devyver   +2 more
doaj   +1 more source

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